血液净化患者导管相关性感染的影响因素

doi:10.20047/j.issn1673-7210.2023.08.29

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Abstract Objective To investigate the factors influencing catheter-associated infections (CRI) in hemodialysis patients. Methods Four hundred and eighty patients who underwent hemodialysis from January 2018 to December 2021 in the Department of Nephrology, the Fifth Medical Center, Chinese People’s Liberation Army General Hospital were selected, the CRI rate of patients was recorded, and the CRI rate of patients with different clinical characteristics was compared. Multi-factor analysis was used to determine the influencing factors of CRI. Results A total of 46 patients out of 480 patients developed CRI, with an infection rate of 9.58%. There were 17 tunnel infections (36.96%), 14 catheter colonization infections (26.67%), 9 exit infections (19.57%), and 6 bloodstream infections (13.04%). There was a statistically significant difference in the rate of CRI in hemodialysis patients with different age, number of punctures, duration of catheter retention, combined diabetes mellitus and hypoproteinemia, length of hospital stay, and application of antimicrobial drugs (P＜0.05). Multifactorial logistic regression analysis showed that, age (OR=2.254), diabetes (OR=2.315), hypoproteinemia (OR=3.015), number of punctures (OR=2.708), duration of indwelling catheter (OR=2.937), length of hospital stay (OR=2.830), and antimicrobial drug application (OR=2.401) were blood purification influencing factors of CRI in patients (P＜0.05). Conclusion Patients with older age, combined diabetes mellitus and hypoproteinemia, more invasive operations, longer hospital stay, and not using antimicrobial drugs are more prone to CRI, so the clinic should pay attention to the management of comorbidities in hemodialysis patients and reduce invasive operations and use antimicrobial drugs reasonably to reduce CRI.

Key words： Blood purification Catheter-related infections Risk factors Central venipuncture

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	ZHANG Juan WANG Tingting GUO Ruirui HU Qiongfen LIU Yang YU Min▲

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ZHANG Juan WANG Tingting GUO Ruirui HU Qiongfen LIU Yang YU Min▲. Factors influencing catheter-associated infections in hemodialysis patients[J]. 中国医药导报, 2023, 20(8): 128-131.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.08.29 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I8/128

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