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| Diagnostic value of ultrasonography in central lymph node metastasis of papillary thyroid carcinoma |
| CHEN Xinxin1 LIANG Yan1 CHEN Ling1 LIU Xiaolin1 LIU Guilian1 LIN Hongguo2 |
1.Department of Ultrasonic, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangdong Provincial Hospital of Chinese Medicine, Guangdong Province, Guangzhou 510120, China;
2.Department of Thyroid Surgery, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangdong Provincial Hospital of Chinese Medicine, Guangdong Province, Guangzhou 510120, China
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Abstract Objective To explore the diagnostic value of ultrasonography in central lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTC). Methods A retrospective analysis was performed on 113 patients with PTC confirmed by pathology who underwent thyroid cancer surgery in Guangdong Provincial Hospital of Chinese Medicine from November 2018 to July 2019. The maximum diameter, shape, edge, aspect ratio, internal echo, calcification, posterior echo, capsule invasion, blood flow signal, and other ultrasonic characteristics were observed; the diagnostic value of ultrasound in CLNM of PTC patients was analyzed. Results Among 113 patients with PTC, preoperative ultrasound showed CLNM in 37 cases, and pathological results showed CLNM in 52 cases. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of preoperative ultrasonic diagnosis of CLNM in PTC patients were 61.5%, 91.8%, 77.9%, 86.5%, and 73.7%, respectively. There were statistically significant differences in maximum nodule diameter, microcalcification, and capsule invasion in patients with or without CLNM (P＜0.05). Conclusion For patients with maximum diameter of PTC nodule ≥1.5 cm, capsule invasion, and microcalcification, cervical CLNM is prone to occur, and preoperative examination and evaluation of cervical lymph nodes should be paid attention to and standardized.
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