|
|
Research progress on the etiology and pathogenesis and traditional Chinese medicine treatment of cancer-related fatigue in lung cancer |
SHEN Yunbo1 YAN Boyu1 LIU Feng1 LAN Xiangyu1 ZHANG Xiaoxue1 LIU Wei2 |
1.Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;
2.Department of Respiratory, the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China
|
|
|
Abstract Cancer-related fatigue (CRF) is the most common complication in patients with lung cancer. The mechanism of its occurrence is unclear. Especially in lung cancer patients after chemotherapy, CRF is more obvious. Traditional Chinese medicine has a profound and comprehensive understanding of lung cancer with CRF. On the etiology and pathogenesis, lung cancer with CRF is manifestation cause of the mutual combination of phlegm, blood stasis, cancer and toxin, and root cause of deficiency of qi, blood and yin and yang. In treatment, invigorating qi, nourishing blood, nourishing yin, warming yang to cure the root cause, resolving phlegm and promoting blood circulation, strengthening the body and detoxifying to cure the symptoms, and combining the characteristic treatment of traditional Chinese medicine, such as traditional Chinese medicine injections, acupuncture and moxibustion, acupoint application. Through improving the immunity of patient, inhibiting tumor cell proliferation, improving bone marrow suppression and other aspect to reduce the symptoms of CRF in patients with lung cancer and improving the quality of life of patients.
|
|
|
|
|
[1] Sung H,Ferlay J,Siegel RL,et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin,2021, 71(3):209-249.
[2] 张剑军,钱建新.中国癌症相关性疲乏临床实践诊疗指南(2021年版)[J].中国癌症杂志,2021,31(9):852-872.
[3] 杜雪菲,杨琼.晚期肺癌患者癌因性疲乏发生现状及危险因素分析[J].中国临床医生杂志,2021,49(8):930- 933.
[4] 吴人杰,谢长生.癌因性疲乏发病机制及治疗的研究进展[J].肿瘤学杂志,2020,26(3):240-244.
[5] 谷珊珊,许云.基于虚劳理论探析癌因性疲乏中医辨治思路[J].国际中医中药杂志,2021,43(11):1154-1157.
[6] 林丽珠,王思愚,黄学武.肺癌中西医结合诊疗专家共识[J].中医肿瘤学杂志,2021,3(6):1-17.
[7] 贾文魁,刘炳男,曹玮,等.从瘀论治癌因性疲乏[J].世界中西医结合杂志,2020,15(6):1152-1155.
[8] 肖志伟,郭苇,林丽珠.癌因性疲乏“虚气留滞”病机特点探索[J].环球中医药,2020,13(12):2050-2053.
[9] 周婷,吴泳蓉,熊家青,等.癌因性疲乏的中医病因探析[J].中华中医药杂志,2022,37(2):982-985.
[10] 张倍源,郭勇.郭勇辨治肺癌相关性疲乏经验介绍[J].新中医,2022,54(4):130-132.
[11] 陈星宇,邓力.从李东垣学术思想论治癌因性疲乏[J].河北中医,2021,43(9):1413-1415,1443.
[12] 王铁军,周丽婷,蔡乐琪,等.基于“阳化气,阴成形”理论探讨益气温阳解毒法在癌因性疲乏治疗中的应用[J].中医药临床杂志,2021,33(11):2060-2063.
[13] 周玲仙,金军,余锡贺.金军教授从脾阴虚论治癌因性疲乏经验[J].河北中医,2021,43(12):2067-2070,2112.
[14] 宁博彪,李宝花,郝淑兰,等.加味补中益气汤治疗非小细胞肺癌术后脾气虚弱型癌因性疲乏的临床研究[J].时珍国医国药,2020,31(11):2685-2688.
[15] 胡静温,杨柳,陈锦秀,等.健脾类方剂治疗癌因性疲乏的Meta分析[J].湖南中医杂志,2021,37(2):115-121.
[16] 沈云博,刘枫,兰向宇,等.温病医家辨治虚劳用药规律探析[J].浙江中医药大学学报,2022,46(6):669-676.
[17] 李妍妍,邹善思,夏利敏.薯蓣丸联合脐灸治疗肺癌癌因性疲乏临床研究[J].新中医,2022,54(5):167-171.
[18] 夏小健,张进科,黄蓓,等.气血舒服散治疗晚期肺癌癌因性疲乏患者气血两虚证36例[J].环球中医药,2021, 14(7):1332-1335.
[19] 崔海波,罗智杰,周伶,等.益气养血补髓膏治疗肺癌虚证患者癌因性疲乏的疗效观察[J].广州中医药大学学报,2021,38(10):2097-2104.
[20] 李正,景欣,张永强.益气养阴方对老年非小细胞肺癌介入化疗患者癌因性疲乏的改善作用[J].河北中医,2019, 41(9):1311-1315,1320.
[21] 杜肖琳,胡广生,许双洁,等.肺复康方治疗中晚期非小细胞肺癌癌因性疲乏的疗效及安全性观察[J].中医药导报,2021,27(10):89-95.
[22] 陆程洁,高静东,刘敏,等.自拟益气温阳方对中晚期非小细胞肺癌患者化疗后骨髓抑制的影响[J].南京中医药大学学报,2018,34(5):465-469.
[23] 刘伟,谢莉莹,姜可园,等.益气温阳颗粒联合贝伐珠单抗对肺癌小鼠肿瘤组织微环境的影响[J].现代中西医结合杂志,2022,31(5):585-590,708.
[24] 赵芳,王振强,张庆江,等.肺瘤消积方对痰瘀互结型非小细胞肺癌患者癌因性疲乏的防治作用研究[J].河北中医,2021,43(6):922-925,929.
[25] 郑巧,姚德蛟,蔡懿.活血复元汤对肺癌患者重度癌因性疲乏及血清CRP、IL-6、ACTH及皮质醇水平的影响[J].四川中医,2021,39(4):61-64.
[26] 张成.祛毒扶正汤联合化疗治疗中晚期非小细胞肺癌的疗效及对患者癌因性疲乏、化疗耐受性的影响[J].四川中医,2019,37(1):107-109.
[27] 刘畅,赵晓珍,王中奇,等.肺岩宁方联合抗瘤增效方对中晚期肺腺癌患者化疗后癌因性疲乏、免疫功能及肿瘤标志物影响的临床研究[J].上海中医药杂志,2019, 53(6):49-53.
[28] 张涛,苏丽群,卢建辉,等.基于网络药理学的参芪扶正注射液治疗癌因性疲乏作用机制探析[J].现代肿瘤医学,2022,30(10):1840-1846.
[29] 熊雪芳,孙德彬.艾迪注射液对晚期非小细胞肺癌化疗增效减毒作用及对血清VEGF及T淋巴细胞亚群的影响[J].中华中医药学刊,2021,39(11):217-220.
[30] 袁超,肖江,秦玮珣,等.针灸治疗癌因性疲乏Meta分析[J].云南中医学院学报,2020,43(4):61-70.
[31] 白平,张国铎,苏立,等.针刺联合改良督灸治疗肺癌化疗后癌因性疲乏的临床研究[J].上海针灸杂志,2022, 41(4):353-358.
[32] 郑香琴,王苗,袁亚芬,等.中药穴位贴敷治疗癌因性疲乏临床研究[J].新中医,2020,52(13):113-118.
[33] 许冬梅.穴位贴敷辅助治疗中晚期肺癌的临床探讨[J].世界复合医学,2021,7(9):79-82.
[34] 刘凤艳,管彩虹.耳穴埋籽对晚期肺癌患者癌因性疼痛和疲乏的控制作用[J].中国现代医生,2020,58(34):129- 132.
[35] 裴燕翔,赵志正,吕雨桐,等.艾叶精油穴位按摩治疗癌因性疲乏的临床研究[J].辽宁中医杂志,2022,49(3):171-174.
[36] 朱吉颖,周红蔚.八段锦治疗肿瘤患者癌因性疲乏的效果观察[J].中国社区医师,2022,38(1):144-146. |
|
|
|