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| Analysis of risk factors for hypercholesterolemia in maintenance hemodialysis patients in Guangdong area |
| XU Yuanzhao QI Airong▲ YANG Jun HAN Xiaowei LUO Denggui |
| Department of Nephrology, Shenzhen Chinese Traditional Medical Hospital, Guangdong Province, Shenzhen 518033, China |
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Abstract Objective To investigate the risk factors of hypercholesterolemia in maintenance hemodialysis (MHD) patients in Guangdong area. Methods From July to September 2017, a total of 1193 MHD patients admitted to 10 hospitals of the Sixth Affiliated Hospitals, Shenzhen Chinese Traditional Medical Hospital, Shenzhen Chinese Traditional Medical Hospital, Dongguan Donghua Hospital, the People′s Hospital of Dongguan City, the Center People′s Hospital of Huizhou City, the Second People′s Hospital of Futian District in Shenzhen, the First People′s Hospital of Shunde, the First People′s Hospital of Zhaoqing City, the Baoan Center Hospital of Shenzhen City, and Guangzhou Hospital of Integrated Traditional and Western Medicine were selected, the risk factors for high cholesterol in MHD patients were analyzed. Results Among the 1193 patients, there were 795 non-hypercholesterolemia patients and 398 hypercholesterolemia patients. Compared with patients with non-hypercholesterolemia, patients with hypercholesterolemia were older, and the levels of platelets, hemoglobin, white blood cells, blood calcium, blood uric acid, total protein, albumin, triglyceride, hypersensitive C-reactive protein, blood β2 microglobulin were higher, e%, serum uric acid, post transdermal blood urea nitrogen, and pre-protein were lower, and had fewer hemofiltrations, fewer useage of alpha and beta receptor antagonists and calcium agent, and less internal embolization (P < 0.05). Gender, age, use of unfractionated heparin, blood uric acid were the independent risk factor for hypercholesterolemia in patients with MHD（P < 0.05）. Conclusion The occurrence of hypercholesterolemia in MHD patients in Guangdong area is related to gender, age, usage of heparin and blood uric acid.
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