急性中度呼吸衰竭经鼻高流量氧疗治疗失败患者的影响因素

doi:10.20047/j.issn1673-7210.2023.05.29

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Abstract Objective To explore the factors influencing the failure of high-flow nasal cannula oxygen therapy (HFNC) for acute moderate respiratory failure. Methods Eighty patients with acute moderate respiratory failure admitted to Changshu First People’s Hospital from January 2021 to September 2021 were collected as research objects, and divided into successful group (43 cases) and failed group (37 cases) according to whether they were converted to non-invasive or tracheal intubation. The general data, prognosis, respiratory circulation index, and pulmonary ultrasound index of the two groups were compared, and the relevant influencing factors were analyzed. Results The lung ultrasound score (LUS) in the successful HFNC group was lower than that in the failed HFNC group, while the diaphragm excursion (DE) was higher than that in the failed HFNC group, and the differences were statistically significant (P＜0.05). Respiratory rate (RR) and mean arterial pressure (MAP) levels in successful HFNC group were lower than those in failed HFNC group, while heart rate (HR) and ROX index were higher than those in failed HFNC group, and the differences were statistically significant (P＜0.05). Logistic regression analysis showed that the increase of RR, MAP and LUS were independent risk factors for treatment failure of HFNC (OR＞1, P＜0.05); the increase of DE, HR, and ROX index were protective factors for treatment failure of HFNC (OR＜1, P＜0.05). Conclusion Lung ultrasound and respiratory circulatory related indexes are poor in patients with treatment failure of HFNC. The increase of RR, MAP and LUS are risk factors for treatment failure of HFNC, while the increase of DE, HR and ROX index are protective factor.

Key words： Pulmonary ultrasound Respiratory circulation Acute respiratory failure High flow nasal cannula oxygen therapy Risk factor

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	HUANG Sheng YU Sun WANG Yilan XU Chunyang▲

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HUANG Sheng YU Sun WANG Yilan XU Chunyang▲. Factors influencing the failure of high-flow cannula oxygen therapy in patients with acute moderate respiratory failure[J]. 中国医药导报, 2023, 20(5): 120-123.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.05.29 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I5/120

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