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Relationship between vitamin A and E levels and pregnancy outcome in patients with gestational hypertension |
YU Hongyun SUN Guiying DING Jianfen |
Department of Obstetrics and Gynecology, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Jiangsu Province, Suzhou 215000, China
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Abstract Objective To investigate the relationship between vitamin A and E levels and pregnancy outcomes in patients with gestational hypertension. Methods A total of 82 patients with gestational hypertension admitted to Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Jiangsu Province (“our hospital” for short) from March 2018 to April 2021 were selected as research group, in addition, 49 healthy pregnant women who underwent routine physical examination during the same period in our hospital were selected as control group. The serum vitamin A and E levels of control group and research group were compared; the research group was divided into poor pregnancy outcome group and good pregnancy outcome group according to pregnancy outcomes, the factors affecting pregnancy outcome were analyzed. The predictive value was evaluated by receiver operating characteristic curve. Results Serum vitamin A, E levels in research group were lower than those in control group, and the differences were statistically significant (P<0.05). There were statistically significant differences in pre-pregnancy body mass index (BMI), disease severity, 24 h urinary protein quantity, blood uric acid, interleukin-6, serum vitamin A, and serum vitamin E between poor pregnancy outcome group and good pregnancy outcome group (P<0.05). Pre-pregnancy BMI, disease severity, 24 h urinary protein quantity, serum vitamin A, and serum vitamin E were the influencing factors of adverse pregnancy outcome in pregnancy-induced hypertension patients (P<0.05). The areas under the curve of serum vitamin A, E single and combined forecast were 0.734, 0.702, and 0.748, respectively. Conclusion Vitamin A and E levels are of great value in predicting adverse pregnancy outcomes in patients with gestational hypertension.
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[1] 李美杰,于峰,周立岩,等.孕早期血清PAPP-A、PLGF、Hcy预测妊娠高血压发生风险[J].中国计划生育学杂志,2022,30(4):914-917.
[2] 费志医,余意,高琴.妊娠高血压疾病胎盘Kif2a、Stat3表达与妊娠结局关系[J].临床和实验医学杂志,2022,21(6):643-646.
[3] 林晓文,曾思繁,修子涵,等.同型半胱氨酸对妊娠高血压疾病的诊断价值[J].贵州医药,2022,46(4):510-512.
[4] 孙芳璨,韩冰,陈友国,等.妊娠期高血压疾病不良结局预测模型的构建及验证[J].中华围产医学杂志,2022,25(3):169-178.
[5] 高晓明.血清ESM-1、TM和sVCAM-1水平对妊娠高血压患者不良妊娠结局的诊断价值[J].检验医学与临床,2022,19(5):648-652.
[6] 岳建宏,刘娟,吉婷,等.妊娠期高血压疾病患者抗心磷脂抗体水平与妊娠结局的关系分析[J].贵州医药,2022, 46(3):393-394.
[7] 郭丽萍,刘梅,纪晓,等.中医药治疗妊娠期高血压疾病研究进展[J].中国中医急症,2022,31(1):181-184.
[8] 张静,王宇光.多巴胺在子痫前期及妊娠期高血压中的作用及其研究的进展[J].心血管康复医学杂志,2022,31(1):111-114.
[9] 金铭,刘晓静,张子怡,等.妊娠期高血压疾病的代谢组学研究进展[J].中国生育健康杂志,2022,33(1):62-67.
[10] 李胤豪,张清月,郭晓宇,等.饲粮添加不同水平的维生素A对肉鸡免疫功能及肝脏、十二指肠组织中一氧化氮代谢的影响[J].动物营养学报,2022,34(1):228-236.
[11] 丁智勇,卜乐,鲁鸿燕,等.非酒精性脂肪性肝病患者血清维生素A水平、肝脏脂肪含量与胰岛素抵抗的相关性分析[J].临床肝胆病杂志,2017,33(12):2361-2365.
[12] 朱青梅,陈金凤,丁楠,等.维生素E治疗非酒精性脂肪性肝病的Meta分析[J].药物流行病学杂志,2021,30(3):174-180.
[13] 谢幸,苟文丽.妇产科学[M].8 版.北京:人民卫生出版社,2013:78-82.
[14] 强娟.妊娠高血压疾病的药物治疗新进展[J].武警后勤学院学报(医学版),2021,30(4):144-147.
[15] 宋伟,李光辉.与肥胖相关的短链脂肪酸水平失衡对妊娠期高血压疾病影响的研究进展[J].医学综述,2021, 27(24):4805-4810.
[16] 董高霞,王晓丽,齐慧.硫酸镁联合拉贝洛尔对妊娠高血压综合征患者炎性应激反应及血管内皮功能的影响[J].实用医院临床杂志,2021,18(3):100-103.
[17] 关琦,张化莲,张珊珊,等.竹节参总皂苷对妊娠期高血压胎盘滋养细胞氧化应激损伤与过度自噬的影响[J].中草药,2021,52(14):4255-4261.
[18] 刘晓霞,巩妮妮.血清25-羟基维生素D在妊娠期高血压患者中的变化及其临床意义[J].实用临床医药杂志,2020,24(9):66-68,72.
[19] 张静,唐国珍,谢江燕,等.妊娠期糖尿病合并高血压患者不良妊娠结局及相关危险因素分析[J].西部医学,2018,30(10):1500-1504.
[20] 倪丽君.妊娠期高血压疾病对妊娠结局的影响以及相关危险因素分析[J].中国妇幼健康研究,2021,32(1):65-69.
[21] 王霞红,梁秋峰,施叶,等.24 h蛋白尿定量在妊娠期高血压疾病中的作用[J].现代妇产科进展,2020,29(1):19-21.
[22] 高雅茹,莫艳丽.妊娠晚期孕妇维生素A水平与妊娠期高血压疾病的关系及维生素A对分娩结局的影响[J].海南医学,2020,31(18):2363-2365.
[23] 高海燕,冯文.超敏C反应蛋白,维生素D、A、E与妊娠期高血压疾病的相关性研究[J].中国性科学,2019,28(1):81-83.
[24] 麻伟博,米鑫.妊娠期维生素A、E营养状态对母体和胎儿结局的影响[J].武警医学,2022,33(3):211-214.
[25] 齐鑫,张小芸.维生素A、D、E与妊娠期高血压疾病患者的相关性及其对预后的评估价值[J].中国妇幼保健,2019,34(20):4648-4651. |
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