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| Research progress of para-aortic prophylactic extended-field irradiation in locally advanced cervical cancer |
| WANG Yuanjing1 WU Yumei2 |
1.Radiation Therapy Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University Beijing Maternal and Child Health Care Hospital, Beijing 100006, China;
2.Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University Beijing Maternal and Child Health Care Hospital, Beijing 100006, China
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Abstract Cervical cancer is the most common malignancy of the female reproductive system. Para-aortic prophylactic extended-field irradiation is recommended for locally advanced cervical cancer patients with positive common iliac or para-aortic lymph nodes. For patients with negative common iliac or para-aortic lymph nodes, the standard treatment is still pelvic radiotherapy with concurrent cisplatin-based chemotherapy. However, para-aortic lymph node metastasis is one of the common causes of treatment failure in locally advanced cervical cancer patients after chemo-radiotherapy. Currently, it is controversial whether to perform prophylactic extended-field irradiation for patients with high-risk factors of para-aortic lymph node metastasis. This article reviews the value of PET/CT in evaluating para-aortic lymph node metastasis of cervical cancer, the effectiveness and indications of prophylactic extended-field irradiation, hoping to provide an important reference for individualized precision radiotherapy for cervical cancer.
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