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Medication rule mining of traditional Chinese medicine for dysmenorrhea based on Ancient and Modern Medical Records Cloud Platform |
LYU Shuzhen1 JU Yuanhong2 XU Jingwen1 SHAO Qi3 GAO Zhiming1 MU Dongmei4 |
1.School of Medical Information, Changchun University of Chinese Medicine, Jilin Province, Changchun 130117, China;
2.School of Public Health, Jilin University, Jilin Province, Changchun 130021, China;
3.School of Information Resource Management, Renmin University of China, Beijing 100872, China;
4.Department of Clinical Research, the First Hospital of Jilin University, Jilin Province, Changchun 130021, China |
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Abstract Objective To explore the medication rules of traditional Chinese medicine for dysmenorrhea based on Ancient and Modern Medical Records Cloud Platform (V2.3.5). Methods The medical records of traditional Chinese medicine for dysmenorrhea collected in Ancient and Modern Medical Records Cloud Platform (V2.3.5) from the inception to October 2021 were retrieved to construct the database of traditional Chinese medicine data. The Ancient and Modern Medical Records Cloud Platform (V2.3.5) and Gephi (V0.9.2) were used to conduct medication statistics, compatibility analysis, cluster analysis, and complex network analysis of traditional Chinese medicine. Results A total of 200 medical records prescriptions were included in this study, involving 246 flavours of drugs, and Angelicae Sinensis Radix was the most frequently used. The medicinal natures were mainly warm, and the medicinal flavours were mainly pungent, sweet, and bitter, which were mainly returned to the liver, spleen, and heart channels. The drug compatibility of “Angelicae Sinensis Radix-Paeoniae Radix Alba” appeared more; five groups of traditional Chinese medicine cluster combinations were obtained. Core drugs included Angelicae Sinensis Radix, Paeoniae Radix Alba, Corydalis Rhizoma, Glycyrrhizae Radix Et Rhizoma, Chuanxiong Rhizoma, etc. Conclusion The treatment of dysmenorrhea by traditional Chinese medicine is mainly based on the medicine of regulating menstruation and relieving pain, removing blood for removing blood stasis, moistening intestines and defecating bowels, tonifying blood and activating blood circulation, supplemented by the medicine of soothing liver and relieving depression, regulating qi and spreading middle, nourishing yin and tonifying kidney, paying attention to both deficiency and excess, treating both manifestation and root cause of disease.
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