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| Research progress on the prevention and treatment of radiation-induced lung injury |
| DONG Guangtong1 ZHANG Xieyu2 HOU Wei2 |
1.Department of Endocrinology Guang′anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;
2.Department of Oncology, Guang′anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
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Abstract Radiotherapy is one of the main methods for treating malignant tumors of the chest. However, it is unavoidable that normal tissues are involved. The lung is a moderately sensitive organ of ionizing radiation and therefore can easily cause radiation-induced lung injury. It mainly manifests itself as two phases, namely the early stage of radiation pneumonitis periad and the irreversible radiation pulmonary fibrosis period, which seriously reduces the quality of the patient′s life and even causes respiratory failure and endangers the life of the patient. Radiation-induced lung injury greatly limits the radiation dose, affects the therapeutic effect, and even forces it to be interrupted. This article reviews the mechanisms of radiation-induced lung injury, modern research, prediction systems, diagnosis, western medicine prevention and treatment.
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