|
|
|
| Application value of percutaneous coronary intervention in ischemic cardiomyopathy |
| TIAN Jiaqi1 LI Jinkuang2▲ |
1.Department of Cardiology, Zhongxiang People′s Hospital, Hubei Province, Zhongxiang 431900, China;
2.Department of Radiology, Zhongxiang People′s Hospital, Hubei Province, Zhongxiang 431900, China |
|
|
|
|
Abstract Objective To investigate the application value of percutaneous coronary intervention (PCI) in the treatment of ischemic cardiomyopathy. Methods Ninety-six patients with ischemic cardiomyopathy admitted to Zhongxiang People′s Hospital from February 2014 to April 2015 were selected and randomly divided into two groups by random coin tossing method, with 48 cases in each group. The control group received conventional drug therapy, on basis of which, the observation group was given PCI. After treatment, the biochemical indexes, cardiac function and adverse events during follow-up in the two groups were compared. Results After treatment for 1 month, the levels of brain natriuretic peptide (BNP), troponin I (TnI) and creatine kinase isoenzyme (CK-MB) in the two groups were all significantly improved compared with those before treatment, the levels of BNP, TnI, CK-MB in the observation group were significantly lower than those of control group, the differences were statistically significant (P ＜ 0.05). After treatment for 1 month, the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDD) in the two groups were all significantly improved compared with those before treatment, the levels of LVEF in the observation group were significantly higher than those of control group, the levels of LVEDD in the observation group were significantly lower than those of control group, the differences were statistically significant (P ＜ 0.05). During follow-up, there was no statistically significant difference of the incidence of acute myocardial infarction between the two groups (P ＞ 0.05); compared with control group, the incidence of heart failure, angina and readmission in the observation group was significantly decreased, the differences were statistically significant (P ＜ 0.05). Conclusion PCI in the treatment of ischemic cardiomyopathy has high application value, which can effectively improve the cardiac function and the levels of BNP, TnI and CK-MB, reduce the incidence of adverse events. It is worthy of clinical promotion.
|
|
|
|
|
|
[1] 欧阳泽伟，贺琳，刘鹏，等.PCI治疗缺血性心肌病对GATA4蛋白表达的影响[J].中国医师杂志，2015，17（9）：1410-1412.
[2] 赵曼，徐予，朱中玉，等.18FDG和99mTc-MIBI双核素心肌显像对冠状动脉闭塞性缺血性心肌病治疗的临床价值[J].中国现代医学杂志，2015，25（30）：53-56.
[3] 闫振娴，周玉杰，赵迎新，等.经皮冠状动脉介入治疗缺血性心肌病合并严重左心功能不全的临床分析[J].心肺血管病杂志，2013，32（4）：418-421.
[4] 陆再英，钟南山，谢毅，等.内科学[M].7版.北京：人民卫生出版社，2008：169，298-299.
[5] 付敏，师聪红，张宝红.冠状动脉介入联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭的临床疗效[J].中西医结合心脑血管病杂志，2014，12（3）：259-260.
[6] 倪沈锋.曲美他嗪治疗缺血性心肌病心衰的疗效及对心功能和心率变异性的影响[J].中国药业，2016，25（19）：23-25.
[7] 杨萃.替米沙坦对缺血性心肌病病人血生化指标及Hcy、IMT的影响[J].中西医结合心脑血管病杂志，2016，14（5）：463-465.
[8] 丁玲岩，马志芳，游美，等.磷酸肌酸钠治疗老年人缺血性心肌病并发顽固性心力衰竭的疗效观察[J].中国基层医药，2015，22（5）：720-722.
[9] 刘鹏，欧阳泽伟，蒲晓群，等.经皮冠状动脉介入治疗在缺血性心肌病患者中的治疗作用[J].中国医药，2013，8（7）：887-889.
[10] 付敏，师聪红，张宝红.冠状动脉介入联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭的临床疗效[J].中西医结合心脑血管病杂志，2014，12（3）：259-260.
[11] 敬锐，林文华.栓塞致扩张型心肌病患者AMI急诊干预一例[J].新医学，2013，44（11）：797-799.
[12] 吴迪，姚克纯，李利，等.应用心肌声学造影评价冠状动脉血运重建术心肌灌注[J].中国超声医学杂志，2013， 29（4）：338-341.
[10] 高艳周，王宏斌，苗博，等.芪苈强心胶囊联合曲美他嗪治疗缺血性心肌病心力衰竭疗效观察[J].现代中西医结合杂志，2016，25（8）：845-847.
[13] 石春光.冠状动脉介入治疗联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭[J].心血管病防治知识：学术版，2017（6）：63-65.
[14] 曾小曼，余再新，王栋，等.经皮冠状动脉介入治疗缺血性心肌病合并严重心功能不全患者疗效观察[J].海南医学，2017，28（3）：475-477.
[15] 石宇杰，易军，陈韵岱.干细胞治疗缺血性心肌病的研究进展[J].中国循证心血管医学杂志，2016，8（11）：1399-1401.
[16] 穆宁晖，杨天睿，苗云波.不完全血运重建联合CRT-P治疗老年缺血性心肌病的临床研究[J/OL].昆明理工大学学报：自然科学版，2016，41（4）：88-91.
[17] 原斌，李子辉.缺血性心肌病经皮冠状动脉介入治疗对改善左心室功能、降低心血管事件发生率的作用[J].昆明医科大学学报，2016，37（6）：57-60.
[18] 黄明剑，温志浩，潘朝锌，等.经皮冠状动脉介入对老年缺血性心肌病患者心功能的影响[J].微创医学，2016， 11（2）：154-156.
[19] 王晓冬，曾波，许春平.冠脉介入治疗缺血性心肌病并左心功能不全的疗效观察[J].微创医学，2015，10（4）：446-448.
[20] 余红，朱锦云，王建安.干细胞治疗缺血性心肌病研究进展[J].中国介入心脏病学杂志，2015，23（5）：286-290.
[21] 刘卫华，赵印平，莫江英，等.冠状动脉介入治疗对缺血性心肌病患者心功能和预后的影响[J].现代中西医结合杂志，2015，24（14）：1486-1488，1512.
[22] Duan W，Geng S，Yang G. Percutaneous coronary intervention in treatment of heart failure derived from geriatric ischemic cardiomyopathy [J]. Chinese Journal of Multiple Organ Diseases in the Elderly，2009，34（1）：145-149.
[23] 刘卫华，赵印平，莫江英，等.冠状动脉介入治疗对缺血性心肌病患者心功能和预后的影响[J].现代中西医结合杂志，2015，24（14）：1486-1512. |
|
|
|
