清热宣肺贴治疗婴幼儿肺炎反复发作的临床效果

doi:10.20047/j.issn1673-7210.2023.02.34

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Abstract Objective To study clinical effect of Qingre Xuanfei Ties in the treatment of recurrent infantile pneumonia. Methods One hundred and six infants with recurrent pneumonia in Second Affiliated Hospital of Xian Medical College from January 2016 to June 2021 were selected and divided into conventional group and experimental group according to random number table method, with fifty three cases in each group. The conventional group was treated with conventional western medicine, while the experimental group was treated with Qingre Xuanfei Ties as an assistant of conventional western medicine. Both groups were treated continuously for one week. Clinical effect, Chinese medicine syndrome score, inflammatory factors [interleukin-4 (IL-4), tumor necrosis factor-α (TNF-α), C reactive protein (CRP)], immune function [immunoglobulin (Ig)A, IgM, IgG], adverse reaction and recurrence of two groups were compared. Results Clinical effect of experimental group was better than that of conventional group, with a statistically significant difference (P＜0.05). Before treatment, there was no significant difference in Chinese medicine syndrome scores between two groups (P＞0.05). After treatment, Chinese medicine syndrome scores of two groups were lower than those before treatment, and experimental group was lower than that conventional group, with statistically significant differences (P＜0.05). Before treatment, there were no significant differences in IL-4, TNF-α, and CRP levels between two groups (P＞0.05). After treatment, IL-4, TNF-α, and CRP levels of two groups were lower than those before treatment, and experimental group was lower than that conventional group, with statistically significant differences (P＜0.05). Before treatment, there were no significant differences in the levels of IgA, IgM, and IgG between two groups (P＞0.05). After treatment, the levels of IgA, IgM, and IgG in the two groups were lower than those before treatment, and experimental group was lower than that conventional group, with statistically significant differences (P＜0.05). There were no significant difference between two groups in the incidence of adverse reactions and the recurrence rate (P＞0.05). Conclusion Qingre Xuanfei Ties is effective in the treatment of recurrent infantile pneumonia. It can reduce the score of Chinese medicine syndrome, reduce inflammatory reaction, improve immune function, and has high safety.

Key words： Infant pneumonia Recurrence Qingre Xuanfei Ties Conventional western medicine treatment Clinical effect Security

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	WU Xinting1 BIAN Weini1▲ ZHENG Lingfang1 MENG Yuancui1 JIA Nan1 CHANG Pan2

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WU Xinting1 BIAN Weini1▲ ZHENG Lingfang1 MENG Yuancui1 JIA Nan1 CHANG Pan2. Clinical effect of Qingre Xuanfei Ties in the treatment of recurrent infantile pneumonia[J]. 中国医药导报, 2023, 20(2): 148-151,159.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.02.34 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I2/148

[1] Abdel Baseer KA，Sakhr H. Clinical profile and risk factors of recurrent pneumonia in children at Qena governorate，Egypt [J]. Int J Clin Pract，2021，75（4）：e13695.
[2] Yun KW，Wallihan R，Juergensen A，et al. Community-acquired pneumonia in children：myths and facts [J]. Am J Perinatol，2019，36（S2）：S54-S57.
[3] Same RG，Amoah J，Hsu AJ，et al. The association of antibiotic duration with successful treatment of community-acquired pneumonia in children [J]. J Pediatric Infect Dis Soc，2021，10（3）：267-273.
[4] 张青，庄承.儿童耐大环内酯类支原体肺炎中西医治疗进展[J].辽宁中医药大学学报，2021，23（2）：172-176.
[5] 宫文浩，王志威，陈莎莎，等.小儿支原体肺炎中医证候病机学研究[J].辽宁中医杂志，2020，47（11）：75-77.
[6] 王蓉燕齐，张蔷，姜琳，等.中医外治法在新生儿肺炎诊疗中的应用[J].中医学报，2020，15（S2）：2.
[7] 王云，高海燕，林小飞.麻杏石甘汤联合小儿清热宣肺贴膏治疗小儿急性支气管炎65例的效果分析[J].武警后勤学院学报：医学版，2019，33（12）：3.
[8] 胡亚美，江载芳.诸福棠实用儿科学[M].北京：人民卫生出版社，2002：167-169.
[9] 中华人民共和国国家健康委员会，国家中医药局.儿童社区获得性肺炎诊疗规范（2019年版）[J].中华临床感染病杂志，2019，12（1）：6-13.
[10] 郑筱萸.中药新药临床研究指导原则[M].北京：中国医药科技出版社，2002：105-110.
[11] Nascimento-Carvalho CM. Community-acquired pneumonia among children：the latest evidence for an updated management [J]. J Pediatr （Rio J），2020，96（Suppl 1）：29-38.
[12] Kutty PK，Jain S，Taylor TH，et al. Mycoplasma pneumoniae among children hospitalized with community-acquired pneumonia [J]. Clin Infect Dis，2019，68（1）：5-12.
[13] Lipsett SC，Hall M，Ambroggio L，et al. Antibiotic choice and clinical outcomes in ambulatory children with community-acquired pneumonia [J]. J Pediatr，2021，12（229）：207-215.
[14] 刘景阳，丁强，张院.小儿支气管肺炎中西医结合临床路径实施研究[J].实用临床医药杂志，2020，24（21）：105- 107.
[15] 党玉兰，刘会伟，温慧，等.儿童肺炎支原体肺炎中药治疗的研究进展[J].医学综述，2021，27（5）：982-986.
[16] 宫文浩，兰天莹，莫清莲，等.肺炎支原体肺炎患儿493例中医证候特点[J].中华中医药杂志，2021，36（10）：4.
[17] 杜建慧，焦曙民，王保安，等.小儿清热宣肺贴膏治疗小儿急性支气管炎Ⅲ期临床试验[J].陕西中医药大学学报，2017，40（4）：59-64.
[18] 嵇达华.自拟宣肺清热汤联合阿奇霉素治疗小儿急性肺炎60例疗效分析[J].中医临床研究，2020，12（14）：3.
[19] 王关涛，李欣，吴振起.中医外治法辅助治疗支原体肺炎有效性的网状Meta分析[J].海南医学院学报，2020， 26（4）：270-276，284.
[20] 张花平，宋贺，张博，等.血清PCT联合CRP、IL-6检测用于鲍曼不动杆菌肺炎临床诊断效能分析[J].临床误诊误治，2020，33（4）：62-67.
[21] 邹姒妮，马战英，李桢，等.阿奇霉素和红霉素对小儿支原体肺炎相关炎症介质及免疫调节状态的效果对比[J].中国医药科学，2021，11（2）：102-105.
[22] 项天河.白细胞介素-6和超敏C反应蛋白水平在支原体肺炎严重程度和预后评估中的意义[J].中国当代医药，2022，29（14）：150-153.
[23] 冀振旭.小儿难治性支原体肺炎免疫指标检测及临床指导价值[J].检验医学与临床，2019，16（20）：3060-3063.
[24] 王凡，陈旭昕，孟激光.重症肺炎患者早期免疫功能变化对疗效及预后的影响[J].国际呼吸杂志，2021，41（18）：1393-1397.
[25] 张萍.清热宣肺化痰平喘汤治疗儿童肺炎痰热闭肺证的临床疗效观察[J].中国中医药科技，2021，28（1）：80- 81.
[26] 乔燕.小儿清热止咳口服液联合雾化吸入用乙酰半胱氨酸溶液治疗小儿支气管肺炎效果观察[J].中国药物与临床，2020，20（18）：3072-3074.
[27] 林史珍，杜方敏，林良静，等.模拟破坏苦杏仁和桃仁品质及酶活性变化研究[J].中国药业，2019，28（15）：5-8.