连续性肾脏替代治疗患者非计划性下机影响因素的meta分析

doi:10.20047/j.issn1673-7210.2023.02.24

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Abstract Objective To systematically evaluate the influencing factors of unplanned interruption in patients on continuous renal replacement therapy (CRRT). Methods The published related literatures in CNKI, Wanfang, VIP, PubMed, EMbase, and other databases were searched by computer. The search time was from the date of creation to March, 2022. The influencing factors of unplanned disembarkation of CRRT were analyzed by meta analysis. Results A total of 16 research papers with 2 289 patients were included in this study. Prolongation of activated partial thromboplastin time (HR=0.939, 95%CI [0.899, 0.992], P＜0.001) was a protective factor for unplanned deactivation of CRRT. High platelet count (HR=1.002, 95%CI[1.000, 1.004], P＜0.001), low blood flow (HR=1.005, 95%CI [1.001, 1.032], P＜0.001), advanced age (OR=3.916, 95%CI[2.736, 5.604], P＜0.001), combined underlying disease (OR=3.386, 95%CI [2.460, 4.660], P＜0.001), ventilator use (OR=3.530, 95%CI[2.051, 6.074], P＜0.001), high hematocrit (HR=1.034, 95%CI[1.016, 1.051], P＜0.001) were risk factors for unplanned disembarkation of CRRT. Conclusion There are many factors influencing the unplanned interruption of CRRT, and nurses’ risk identifi-cation ability should be improved to enhance the ability of anticipatory care and improve the quality of CRRT.

Key words： Continuous renal replacement therapy Unplanned interruption Influence factor Meta analysis

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	CHEN Yuqian LI Wenxiong▲ YANG Na

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CHEN Yuqian LI Wenxiong▲ YANG Na. Meta analysis of influencing factors of unplanned interruptionin in patients on continuous renal replacement therapy[J]. 中国医药导报, 2023, 20(2): 105-108,113.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.02.24 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I2/105

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