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Value of combined monitoring of bispectral index, transcranial Doppler, and intracranial pressure in prognosis assessment of severe craniocerebral injury |
DING Lili LIU Mengru SUN Haijun▲ |
Department of Critical Care Medicine, the First People’s Hospital of Suqian, Jiangsu Province, Suqian 223800, China |
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Abstract Objective To explore the value of combined monitoring of bispectral index (BIS), transcranial Doppler (TCD), and intracranial pressure (ICP) in prognosis assessment of severe craniocerebral injury. Methods A total of 80 patients with ICP with severe craniocerebral injury admitted to the First People’s Hospital of Suqian, Jiangsu Province from November 2018 to November 2021 were selected and divided into good prognosis group (59 cases) and poor prognosis group (21 cases) according to the Glasgow coma scale score 21 days after treatment. Basic data, BIS, ICP, and TCD data (mean blood flow velocity [Vm]) of all patients were collected, and sorted out. Logistic regression model was used to analyze the related factors of poor prognosis in patients with severe craniocerebral injury, and receiver operating characteristic curve (ROC) was used to evaluate the value of combined monitoring of BIS, TCD, and ICP in the prognosis assessment of severe craniocerebral injury. Results ICP in the poor prognosis group were higher than those in the good prognosis group, BIS, and Vm were lower than those in the good prognosis group (P<0.05). The results of multivariate analysis showed that BIS, ICP, and Vm were influencing factors for poor prognosis of patients with severe craniocerebral injury (P<0.05). The area under the curve of BIS, Vm, and ICP combined predicted the prognosis of severe craniocerebral injury was higher than that of each prediction alone (P<0.05). Conclusion The combined monitoring of BIS, TCD, and ICP has a high value in the prognosis assessment of patients with severe craniocerebral injury, and worthy of clinicall attention.
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