不同Ki-67表达状态乳腺癌临床病理特征及MRI表现对比分析

doi:10.20047/j.issn1673-7210.2023.02.05

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Abstract Objective To explore clinicopathological characteristics and MRI manifestations of breast cancer with different Ki-67 expression and compare their difference. Methods A total of 205 patients with non-special invasive breast cancer diagnosed by pathology were collected in Tumour Hospital Affiliated to Xinjiang Medical University from January 2014 to December 2018. Ki-67≥20% was used as the high expression group (146 cases), Ki-67<20% was used as the low expression group (59 cases). The clinicopathological characteristics, MRI manifestations and parameters(the maximum diameter of tumor, apparent diffusion coefficient [ADC] value, and early enhancement rate) between two groups were compared. Results There were no significant differences in lymph node metastasis and tumor shape between two groups (P＞0.05); while there were significant differences in histological grade, estrogen receptor, progesterone receptor, human epidermal growth factor receptor-2, p53 expression, tumor margin, internal enhancement characteristics, time-signal intensity curve type, the maximum diameter of tumor, ADC value, and early enhancement rate between two groups. Conclusion There are certain difference in clinicopathological characteristics and MRI manifestations of breast cancer with different Ki-67 expression, which is helpful to guide the clinical development of treatment strategies.

Key words： Breast cancer Pathology Ki-67 MRI

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	WANG Yanlong1 ZHU Lina2▲ XIAO Lan3 LI Xing2

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WANG Yanlong1 ZHU Lina2▲ XIAO Lan3 LI Xing2. Comparative analysis of clinicopathological characteristics and MRI manifestations of breast cancer with different Ki-67 expression[J]. 中国医药导报, 2023, 20(2): 26-29.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.02.05 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I2/26

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