|
|
Professor Sun Weizheng’s experience in treating chronic aplastic anemia in children |
WU Yuantian1 SUN Weizheng2 YUSUN-Wanqi3 WANG Jinhuan2 |
1.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150000, China;
2.Department of Hematology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150000, China;
3.College of Chinese Medicine, Anhui University of Chinese Medicine, Anhui Province, Hefei 230000, China |
|
|
Abstract Aplastic anemia is a kind of hematological disease characterized by pancytopenia and decline of hematopoietic function of bone marrow, and its clinical manifestations are anemia, hemorrhage, repeated infection and so on. This paper introduces Professor Sun Weizheng’s clinical experience in the treatment of chronic aplastic anemia in children. Professor Sun believes that marrow depletion due to kidney deficiency is the core pathogenesis of the disease. Children’s delicate viscera, easy to transmit after feeling evil,and the physiological and pathological characteristics of being easy to injure yin make the performance of the disease in children more complex than that in adult patients. in addition, “blood stasis” and “heat” also have an important impact on the development and evolution of the disease. According to the etiology and pathogenesis of this disease, Professor Sun carefully examines yin and yang, distinguishes specimens, takes tonifying the kidney as the core, pays attention to taking care of children’s spleen and stomach, integrates the treatment of blood stasis and prevention of blood stasis in the whole process of treatment, and pays attention to the influence of daily life and emotions on the disease, and had excellent clinical effect.
|
|
|
|
|
[1] Jeong DC,Chung NG,Kang HJ,et al. Epidemiology and clinical long-term outcome of childhood aplastic anemia in Korea for 15 years: retrospective study of the Korean Society of Pediatric Hematology Oncology (KSPHO) [J]. J Pediatr Hematol Oncol,2011,33(3):172-178.
[2] 韩雪,乔晓红.儿童再生障碍性贫血的病因及流行病学研究进展[J].中国小儿血液与肿瘤杂志,2021,26(1):60- 63.
[3] 吴迪炯,周郁鸿,沈一平.慢性再生障碍性贫血中医认识及优势进展[J].中华中医药学刊,2012,30(3):500-502.
[4] 陈信义,陈珮.中医治疗血液病名家学术观点撷菁[J].北京中医药,2021,40(5):466-469.
[5] 王金环,代月,张炫娜,等.补肾生血法治疗慢性再生障碍性贫血的疗效及对CD11a细胞粘附分子的影响[J].时珍国医国药,2020,31(6):1302-1304.
[6] 王德好,丁晓庆,刘军霞,等.再障膏方对再生障碍性贫血小鼠FOXP3、GATA-3、T-bet、Notch1蛋白表达及Treg/ Th17的影响[J].环球中医药,2021,14(4):568-572.
[7] 农志飞,韦杏,杨振亚,等.小儿生理病理特点在中医儿科学教学中的重要性分析[J].广西中医药大学学报,2020, 23(3):120-122.
[8] 雍延礼,刘丽梅,孙伟正.“阳虚易治、阴虚难调”机理探讨[J].中医药信息,2009,26(1):11-12.
[9] 郭芳.补髓生血汤联合环孢素A软胶囊及司坦唑醇片治疗慢性再生障碍性贫血临床研究[J].新中医,2019,51(10):204-208.
[10] 韩惠杰,刘巧丽,陆瑛瑛,等.慢性再生障碍性贫血“阳虚易治,阴虚难调”理论探讨[J].陕西中医,2021,42(3):347-349.
[11] 郝晶,孙伟正,高明洁,等.补髓生血颗粒治疗慢性再生障碍性贫血[J].中医学报,2020,35(8):1775-1778.
[12] 孙凤,雍彦礼,王金环,等.补髓生血颗粒治疗慢性再生障碍性贫血的疗效及对Th17细胞和IL-23的影响[J].中国中西医结合杂志,2016,36(7):885-887.
[13] 沈凤麟,王金环,陈文婷,等.基于寒区发病特点的龙江医家血液病中医辨治思维与实践[J].世界科学技术-中医药现代化,2020,22(5):1380-1385.
[14] 崔春婷.观察中药黄芪的药理作用及临床应用效果[J].首都食品与医药,2020,27(5):188-189.
[15] 马艳春,范楚晨,冯天甜,等.茯苓的化学成分和药理作用研究进展[J].中医药学报,2021,49(12):108-111.
[16] 张小敏,朱玲玲,肖扬.再生障碍性贫血相关信号通路的研究进展[J].中国病理生理杂志,2021,37(11):2094- 2099.
[17] 于孙婉琪,谷梦宇,史文萱,等.孙伟正教授从肾论治非重型再生障碍性贫血经验撷英[J].中医药信息,2022, 39(3):25-28.
[18] 李梓盟,张佳彦,李菲,等.白花蛇舌草抗肿瘤化学成分及药理作用研究进展[J].中医药信息,2021,38(2):74- 79.
[19] 罗正凯,郝晶,王小东,等.孙伟正应用猪苓治疗血液病经验与学术观点[J].中华中医药杂志,2016,31(3):881- 883.
[20] 连小龙,令颖,张尚龙,等.甘草有效成分抗肿瘤作用机制及联合抗肿瘤研究进展[J].中国实验方剂学杂志,2022, 28(11):238-245.
[21] 李亚群,田云龙,王靖.从“脾主困”论治儿童功能性消化不良[J].中国中西医结合儿科学,2021,13(6):542- 545.
[22] 陈锦明,雷黄伟,林雪娟,等.“互联网+”中医健康管理模式的服务现状与对策研究[J].福建中医药,2020,51(5):62-63.
[23] 马兆辰,陈莹,白家莹,等.《小儿药证直诀》用药特色[J].福建中医药,2021,52(10):31-34.
[24] 陈静.儿童获得性非重型再生障碍性贫血中西医结合诊疗专家共识[J].中国小儿血液与肿瘤杂志,2021,26(5):257-260.
[25] 金焱,刘欣,汪安友,等.55例初诊再生障碍性贫血患者临床特征分析[J].中国医药科学,2021,11(5):230-233.
[26] 王居义,邹维志,陈玥琪,等.沈金鳌情志病学术思想之探骊[J].湖南中医杂志,2022,38(4):111-115. |
|
|
|