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| CiteSpace-based visualization of the current status of the application of Sinomenine in Chinese medicine research |
| ZHANG Zixuan1 AN Yi1 ZHANG Xinwen1 ZHAO Xin1 ZHANG Xieyu1 ZHAO Jiahe2 CAO Wei3 |
1.Guang’anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing 100053, China;
2.School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
3.Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China |
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Abstract Objective To analyze the current status and future development trend of Chinese medicine related research on Sinomenine in the past 20 years at home and abroad by scientific knowledge mapping methods. Methods The research literatures related to Sinomenine from January 2001 to April 2022 included in China Knowledge Network and Web of Science databases were searched, and the authors, countries, institutions, and keywords were visualized analyzed by CiteSpace software. Results A total of 973 Chinese literatures and 264 English literatures were obtained. The number of publications on Sinomenine research had shown a fluctuating upward trend in the last 20 years. Zhou Liling and Liu Liang were the authors with the highest number of publications in English and Chinese, respectively. The publishing institutions were concentrated in China, mainly in Guangzhou University of Chinese Medicine, but there was a lack of cooperation between teams and institutions. Keywords analysis showed that Sinomenine, proliferation, apoptosis, rat, and cyanophylline were the hotspots of cyanophylline research in Chinese, cell expression, apoptosis, activation, metabolism, inhibition, rheumatoid arthritis, mouse, and proliferation were the hotspots of research in English, and domestic and foreign research trends focused on apoptosis and cell proliferation. Conclusion At present, the field of Cyanophylline is in the rising stage of development, and the research hotspots and trends are apoptosis and cell proliferation, but there is little cooperation among team institutions, and the communication and cooperation should be increased, which is conducive to promoting the long-term development of cyanophylline.
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