CT评分及血清学指标联合预测颅脑损伤早期临床转归的价值

doi:10.20047/j.issn1673-7210.2022.35.16

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Abstract Objective To study the value of CT score and serological indexs in predicting early clinical outcome of craniocerebral injury. Methods Clinical data of 118 patients with craniocerebral injury admitted to Wuxi Ninth People’s Hospital of Jiangsu Province and Yangquan Coal Industry (Group) General Hospital of Shanxi Province from January 2019 to December 2021 were retrospectively analyzed, and they were divided into good prognosis group (76 cases) and poor prognosis group (42 cases) according to the Glasgow outcome scale-extended score at three months after operation. The clinical data, preoperative CT scores, and serum levels of interleukin (IL)-1β, IL-6, and S100 calcium-binding protein B (S100B) were compared between the two groups, and the influencing factors of early clinical outcome in patients with craniocerebral injury and their predictive value for outcome were further analyzed. Results The proportion of Glasgow coma scale (GCS) score of 3-8 points, CT score, and serum levels of IL-1β, IL-6, and S100B in the poor prognosis group were higher than those in the good prognosis group, the differences were statistically significant (P＜0.05). The results of multivariate analysis showed that GCS score of 3-8 points, CT score, and serum levels of IL-1β, IL-6, and S100B were the influential factors for early poor outcome of patients with craniocerebral injury (P＜0.05). The results of the receiver operator characteristic curve showed that CT score and serum levels of IL-1β, IL-6, and S100B alone and in combination all had the value in predicting the early poor outcome of patients with craniocerebral injury (area under the curve＞0.5, P＜0.05). Conclusion CT score combines with IL-1β, IL-6, and S100B has high value in predicting early outcome of patients with craniocerebral injury

Key words： Craniocerebral injury Clinical outcome CT score Serological index Combined prediction

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	YUE Shengkui1 LIU Haobo2 PAN Donghong2 FANG Wei1 XIA Tian1

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YUE Shengkui1 LIU Haobo2 PAN Donghong2 FANG Wei1 XIA Tian1. Value of the combine of CT score and serological indexs in predicting early clinical outcome of craniocerebral injury[J]. 中国医药导报, 2022, 19(35): 70-73.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.35.16 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I35/70

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