肠道预适应对门静脉高压症术后早期恢复质量的影响

doi:10.20047/j.issn1673-7210.2022.34.42

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Abstract Objective To investigate the impact of bowel preadaptation on the quality of early recovery after surgery for portal hypertension. Methods Ninety patients diagnosed with portal hypertension undergoing surgery from April 2020 to September 2021 in the Department of Hepatobiliary and Pancreatic Surgery, Huai’an First Hospital Affiliated to Nanjing Medical University were selected for the study and they were divided into experimental group and control group by random number table method，with 45 cases in each group. The experimental group received intestinal preadaptation, while the control group was prepared according to the conventional preoperative nutrition, and the two groups were compared in terms of postoperative intestinal function recovery and postoperative recovery quality. Results The rates of postoperative abdominal distension, abdominal pain, nausea, and vomiting in the experimental group were lower than those in the control group, and the differences were statistically significant (P＜0.05). The time to the first feeding of fluid and the time to the resumption of anal venting in the experimental group were shorter than in the control group, and the differences were statistically significant (P＜0.05). On postoperative 5 d, albumin and serum prealbumin were higher in both groups than on postoperative 1 d, while those in the experimental group were higher than those in the control group, with statistically significant differences (P＜0.05). The differences were statistically significant when comparing QoR-15 scores, leukocytes, and C-reactive protein levels between groups, time, and interaction between the two groups (P＜0.05). Among them, the level of QoR-15 score was higher in both groups at 7 d postoperatively than at 1 and 3 d postoperatively, while the levels of leukocytes and C-reactive protein were higher than at 1 d postoperatively and lower than at 3 d postoperatively; the indexes were higher in both groups at 3 d postoperatively than at 1 d postoperatively, and the differences were statistically significant (P＜0.05). The QoR-15 score of the experimental group was higher than that of the control group at 7 d postoperatively, while the leukocytes and C-reactive protein of the experimental group were lower than those of the control group, with statistically significant differences (P＜0.05). Conclusion Bowel preadaptation in patients with portal hypertension can reduce the occurrence of postoperative gastrointestinal dysfunction in patients, improve nutritional status, and enhance the quality of early recovery.

Key words： Hypertension Portal Enteral nutrition Bowel preconditioning Quality of recovery

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	JIN Shanshan1 XU Qin2▲

Cite this article:

JIN Shanshan1 XU Qin2▲. Effect of bowel preadaptation on the quality of early recovery after surgery for portal hypertension[J]. 中国医药导报, 2022, 19(34): 182-185.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.34.42 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I34/182

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