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Value of ultrasound-guided fine needle aspiration cytology combined with contrast-enhanced ultrasound in the qualitative diagnosis of thyroid nodules |
QIAO Xudong |
Department of Ultrasound Medicine, Ninth Hospital of Xi’an, Shaanxi Province, Xi’an 710054, China |
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Abstract Objective To investigate the value of ultrasound-guided thyroid fine needle aspiration cytology (US-FNAB) and contrast-enhanced ultrasound (CEUS) in the qualitative diagnosis of thyroid imaging reporting and data system (TI-RADS) class 4 thyroid nodules. Methods The clinical data of 298 patients with TI-RADS class 4 thyroid nodules admitted to Ninth Hospital of Xi’an from January 2019 to December 2021 were retrospectively analyzed, a total of 326 thyroid nodules were confirmed by postoperative pathological examination, included 182 malignant nodules and 144 benign nodules. All patients underwent CEUS examination, US-FNAB examination, and combined US-FNAB and CEUS examination. Postoperative pathological examination as the gold standard, the benign and malignant detection of US-FNAB, CEUS, and their combined examination, the diagnostic value of US-FNAB, CEUS, and their combined examination were compared between the two groups, and the characteristics of CEUS perfusion and US-FNAB needle sensation of benign and malignant nodules were recorded. Results CEUS detected 180 cases of malignant TI-RADS class 4 thyroid nodules and 146 cases of benign TI-RADS class 4 thyroid nodules; US-FNAB detected 181 cases of malignant and 145 cases of benign; 208 cases of malignant and 118 cases of benign by jointly detected. The results of CEUS, US-FNA, and combined examination were consistent with those of postoperative pathological examination. The perfusion of CEUS in malignant showed low enhancement, while that in benign showed high enhancement or equal enhancement. In the malignant, the proportion of needle sensation in the US-FNAB was 81.77%, which was higher than 19.31% in the benign group (P<0.05). Conclusion CEUS, US-FNA, and combined examination can effectively determine the benign and malignant of TI-RADS class 4 thyroid nodules, CEUS-enhanced features and US-FNAB acupuncture can provide the basis, and the combined examination of US-FNAB and CEUS have high sensitivity in the identification of benign and malignant, and have high diagnostic value.
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[1] 李新彦,盖曰秀.超声成像联合McGill甲状腺结节评分对甲状腺良恶性结节鉴别诊断价值研究[J].中国医学装备,2017,14,30(3):70-72.
[2] 中华医学会超声医学分会浅表器官和血管学组,中国甲状腺与乳腺超声人工智能联盟,詹维伟,等.2020甲状腺结节超声恶性危险分层中国指南:C-TIRADS[J]中华超声影像学杂志,2021,30(3):185-200.
[3] 李柠肖,邝永卫,陈君耀,等.CEUS定量分析联合血清uPA、Hpa检测在甲状腺结节性质判断中的价值[J].山东医药,2019,59(16):44-47.
[4] 陈娅娅,吕一骏,严赟,等.超声引导下细针抽吸联合液基细胞学对甲状腺结节的诊断价值[J].中国超声医学杂志,2020,36(6):485-488.
[5] 周建桥,詹维伟.2020年中国超声甲状腺影像报告和数据系统(C-TIRADS)指南解读[J].诊断理论与实践,2020,10(4):587-593.
[6] 施红卫,王辉阳,邓华东,等.超声造影联合细针穿刺活检及BRAF基因检测对TI-RADS 4类甲状腺结节的诊断价值[J].中华超声影像学杂志,2022,31(3):214-219.
[7] 周一帆,王建华,徐书杭.甲状腺细胞病理学Bethesda报告系统的更新及研究进展[J].国际内分泌代谢杂志,2020, 40(3):175-178.
[8] 章思伟,孙书菊,涂昊.超声引导下细针穿刺细胞学检查与超声造影在良恶性甲状腺结节鉴别诊断中的价值[J].中国医师进修杂志,2019,42(5):388-391.
[9] 刘如玉,张波.超声在甲状腺结节和甲状腺癌全程管理中的作用[J].中国医学科学院学报,2017,39(3):445-450.
[10] 何晓娜,张小鹏,王斌儒,等.甲状腺结节性疾病超声诊疗的研究进展[J].医学综述,2018,24(12):2467-2475.
[11] 何莉莉,柏根基.SE联合SMI检查鉴别甲状腺结节的临床分析[J].临床肿瘤学杂志,2022,27(3):250-254.
[12] 林文金,薛恩生,刘世友,等.高频超声对伴环形钙化甲状腺结节的诊断价值[J].中国超声医学杂志,2018,34(2):105-107.
[13] 王子璋,李继锋,孙海凤,等.TI-RADS分类系统在甲状腺结节诊断中的应用价值[J].现代肿瘤医学,2019,27(9):1522-1525.
[14] 李玲,吕国荣,沈浩霖,等.TI-RADS分类超声客观评价体系的建立和应用[J].中国医学影像技术,2017,33(5):698-702.
[15] 陶菁,彭清海.超声造影技术在甲状腺良恶性结节鉴别中的应用[J].医学综述,2018,24(1):170-174.
[16] 陶玲玲,樊金芳,李伟伟,等.甲状腺结节超声造影及相关病理形态结构研究[J].中国医学计算机成像杂志,2019, 25(1):63-66.
[17] 范雪,候雪琴,杨凌菲,等.超声造影对甲状腺可疑结节的定性诊断价值[J].新疆医科大学学报,2017,40(1):26-29,34.
[18] 朱敏敏,许妍,肖潇,等.实时超声弹性成像调整C- TIRADS 4类甲状腺结节的临床价值[J].临床超声医学杂志,2022,24(8):583-587.
[19] 王珏,何杰.甲状腺细针穿刺细胞学诊断中滤泡性肿瘤的临床病理分析[J].临床与实验病理学杂志,2022,38(7):864-867.
[20] 华威,李嘉瑶,王超萃,等.甲状腺细针穿刺细胞学误诊及漏诊的临床病理分析[J].哈尔滨医科大学学报,2020, 54(6):606-611.
[21] 谭兴利,彭世义,周志英.超声引导细针穿刺细胞学检查对TI-RADS4类甲状腺结节的价值[J].外科理论与实践,2019,24(1):75-78.
[22] 郑博文,李海凤,吴涛,等.甲状腺结节细针穿刺活检假阳性诊断的细胞学及超声特征分析[J].中华超声影像学杂志,2021,30(12):1058-1063.
[23] 彭光生,陈怡.甲状腺结节过度超声诊断及应对策略[J].中国超声医学杂志,2020,36(10):883-886.
[24] 章美武,张燕,范晓翔,等.甲状腺细针穿刺细胞学联合BRAF基因检测的诊断价值[J].介入放射学杂志,2017, 26(7):622-626.
[25] 胡剑秋,黄钰清,陈祥慧,等.超声造影联合细针穿刺手感对甲状腺乳头状癌的诊断价值[J].武警医学,2021, 32(9):776-780.
[26] 吴丽娟,刘婷,付霞.超声弹性成像联合常规超声对甲状腺结节的诊断价值[J].中国医学创新,2021,18(32):160-164.
[27] 彭贵平.彩色多普勒超声对甲状腺结节性病变的诊断价值[J].中国当代医药,2021,28(10):173-176.
[28] 刘小伟,陈敏,秦文羚.超声弹性成像检查对甲状腺结节良恶性的诊断价值研究[J].当代医学,2020,26(29):83-85
[29] 蔡添凤.甲状腺结节良恶性病变鉴别诊断中甲状腺钙化超声分型的应用及其准确性分析[J].中国医学创新,2020,17(4):117-120. |
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