肝脏局灶性结节增生的影像表现

doi:10.20047/j.issn1673-7210.2022.34.32

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Abstract Objective To investigate the CT and MRI imaging manifestations of focal nodal hyperplasia (FNH) of the liver. Methods The clinical and imaging data of 27 patients with FNH confirmed by surgery and pathology in the First People’s Hospital of Zhaoqing and the Affiliated Hospital of Zhaoqing Medical College from February 2015 to October 2020 were analyzed, and their imaging manifestations were analyzed. Results CT and MRI of typical FNH patients showed central fiber scar of the lesion with high signal intensity on T2WI. In contrast-enhanced arterial phase, the lesion was significantly enhanced except fibrous scar, while in delayed phase, contrast agent filling was found in fibrous scar. Atypical FNH showed various imaging manifestations, CT scan showed low density, large blood supply arteries in or around the enhanced artery lesions, rich “radial” vessels of different thickness in portal phase and delayed phase lesions, and the strengthening mode was “central flowering”. MRI showed low signal on T1WI and high signal on T2WI. The enhancement mode of contrast-enhanced scan was basically the same as that of CT. Conclusion The CT and MRI findings of typical FNH have certain characteristics and are not difficult to diagnose clinically; however, atypical FNH can be steatosis and has no “central fibrous scar”, so it is still difficult to accurately diagnose atypical FNH in clinical work. The “central flowering” enhancement in CT and MRI may help to improve the diagnostic rate of atypical FNH.

Key words： Liver tumor Focal nodular hyperplasia Multi-slice spiral CT Magnetic resonance imaging

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	QIU Ganbin1 LIAO Weixiong1 WEN Zhongyan2 LIU Yonghui2 CHEN Jincan2▲

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QIU Ganbin1 LIAO Weixiong1 WEN Zhongyan2 LIU Yonghui2 CHEN Jincan2▲. Imaging manifestations of focal nodular hyperplasia of the liver[J]. 中国医药导报, 2022, 19(34): 140-143,153.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.34.32 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I34/140

[1] Zviniene K，Zaboriene I，Basevicius A，et al. Comparative diagnostic value of computed tomography and contrastenhanced ultrasonography in diagnosis of focal liver lesions [J]. Medicina（Kaunas），2009，45（10）：751-763.
[2] Bioulac-Sage P，Balabaud C，Wanless I. WHO Classification tumors of the digested system [M]. Lyon：IARC Press，2010：198-204.
[3] 李增荣，陈本宝.肝脏局灶性结节增生的MSCT诊断[J].医学影像学杂志，2014，24（6）：973-976.
[4] Levy AD. Focal Nodular Hyperplasia：Findings at State-of- the-Art MR Imaging，US，CT，and Pathologic Analysis：Invited Commentary [J]. Radiographics，2004，24（1）：18-19.
[5] 王成，刘承利，孔亚林，等.四例不典型肝局灶性结节增生的影像学特点[J].肝胆胰外科杂志，2021，33（11）：666- 671.
[6] 陈燕，周碧，申玉兰，等.肝脏局灶性结节增生的多层螺旋CT和MRI表现及病理基础[J].中华实用诊断与治疗杂志，2017，31（12）：1217-1219.
[7] Li W，Lv XZ，Zheng X，et al. Machine Learning-Based Ultrasomics Improves the Diagnostic Performance in Differentiating Focal Nodular Hyperplasia and Atypical Hepatocellular Carcinoma [J]. Front Oncol，2021，11：544979.
[8] Takeda N，Tsuchiya A，Natsui K，et al. Novel Strategy for Diagnosis of Focal Nodular Hyperplasia Using Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid：Enhanced Magnetic Resonance Imaging and Magnetic Resonance Elastography [J]. Case Rep Gastroenterol，2021，15（2）：507-512.
[9] Takahashi Y，Dungubat E，Kusano H，et al. Application of Immunohistochemistry in the Pathological Diagnosis of Liver Tumors [J]. Int J Mol Sci，2021，22（11）：5780.
[10] Auer TA，Walter-Rittel T，Geisel D，et al. HBP-enhancing hepatocellular adenomas and how to discriminate them from FNH in Gd-EOB MRI [J]. BMC Med Imaging，2021，21（1）：28.
[11] Jia S，Wang X，Radiology DO. CT and MRI Findings and the Prognosis of Focal Nodular Hyperplasia [J]. Chinese Journal of CT and MRI，2018，36 （6）：15-23.
[12] Turowski C，Feist H，Alzen G，et al. Conversion of a neonatal hepatic hemangioma to focal nodular hyperplasia [J]. Pathol Int，2009，59（4）：251-254.
[13] 陈茂红.CT与MRI诊断肝脏局灶性结节增生的价值[J].医疗装备，2021，34（16）：21-22.
[14] 李思振.CT与MRI在肝脏局灶性结节状增生诊断中的效果及准确率评价[J].现代医用影像学，2021，30（10）：1842-1845.
[15] Ben Ismail I，Zenaidi H，Jouini R，et al. Pedunculated hepatic focal nodular hyperplasia：A case report and review of the literature [J]. Clin Case Rep，2021，9（6）：e04202.
[16] 廖立，黄仲奎，韩秋丽，等.无瘢痕的FNH与肝腺瘤的CT鉴别诊断[J].临床放射学杂志，2019，38（4）：642-646.
[17] 辜红先，徐建锋，樊树峰.肝脏局灶性增生结节不典型MR影像表现并文献复习[J].临床放射学杂志，2021，40（10）：2029-2033.
[18] Bilreiro C，Soler JC，Ayuso JR，et al. Diagnostic value of morphological enhancement patterns in the hepatobiliary phase of gadoxetic acid-enhanced MRI to distinguish focal nodular hyperplasia from hepatocellular adenoma [J]. Radiol Med，2021，126（11）：1379-1387.
[19] Ding Z，Lin K，Fu J，et al. An MR-based radiomics model for differentiation between hepatocellular carcinoma and focal nodular hyperplasia in non-cirrhotic liver [J]. World J Surg Oncol，2021，19（1）：181.
[20] Park HJ，Byun JH，Kang JH，et al. Value of discrepancy of the central scar-like structure between dynamic CT and gadoxetate disodium-enhanced MRI in differentiation of focal nodular hyperplasia and hepatocellular adenoma [J]. Eur J Radiol，2021，139：109730.
[21] 丁建林，易旦冰，梁韬，等.肝局灶性结节增生：64层螺旋CT双动脉期的价值[J].实用放射学杂志，2013，29（7）：1105-1107.
[22] Grazioli L，Morana G，Federle MP，et al. Focal Nodular Hyperplasia：Morphologic and Functional Information from MR Imaging with Gadobenate Dimeglumine [J]. Radiology，2001，221（3）：731-739.
[23] Vasireddi AK，Leo ME，Squires JH. Magnetic resonance imaging of pediatric liver tumors [J]. Pediatr Radiol，2022， 52（2）：177-188.
[24] 刘晓梅，孙英杰，刘秀民，等.纤维板层型肝癌三例磁共振成像表现及文献复习[J].实用医学影像杂志，2015， 16（3）：51-53.
[25] 赵德利.动态增强CT在鉴别诊断肝脏血管肉瘤和血管瘤中的价值[J].放射学实践，2016，31（8）：764-767.