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Clinical characteristics and distribution of traditional Chinese medicine syndrome elements of Sangqi Qingxuan Granules in treating hypertension |
REN Weiquan1 FAN Jiarong2 ZHANG Gaoyu2 HE Qing2 LIAO Jiangquan3 HUANG Li3 LI Lin3▲ |
1.Department of Traditional Chinese Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
2.Beijing University of Chinese Medicine, Beijing 100029, China;
3.Department of Cardiology of Integrated Chinese and Western Medicine, China-Japan Friendship Hospital, Beijing 100029, China |
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Abstract Objective To evaluate the clinical characteristics and distribution of traditional Chinese medicine syndrome elements of patients with hypertension treated by Sangqi Qingxuan Granules. Methods From January 2018 to December 2019, a total of 150 hypertensive patients who were treated with Sangqi Qingxuan Granules by Professor Huang Li in China-Japan Friendship Hospital were selected for the collection of clinical general data and syndrome element evaluation. The distribution of symptoms, tongue and pulse, syndrome elements were observed. Results A total of 150 questionnaires were distributed and 122 valid questionnaires were collected. The gender distribution of the population was mostly male (62 cases, accounting for 50.8%), the age distribution was mostly patients under 60 years old (78 cases, 63.93%), the body weight was more obese (54 cases, accounting for 44.26%), and the hypertension grade was more common in grade 1 (74 cases, accounting for 60.66%). In terms of traditional Chinese medicine syndromes, dizziness, headache, poor sleep, more dreams and dry stools were the most common symptoms. The patients were mostly characterized by pink tongue, thin fur, stringy and thready pulse, and syndrome of hyperactivity of yang. Cluster analysis showed three patterns of combination of syndrome elements: hyperactivity of yang; yin deficiency; blood stasis, qi deficiency, qi stagnation, phlegm, dampness, heat. Conclusion Sangqi Qingxuan Granules is effective in the treatment of grade 1 hypertension, especially for patients with syndrome of yin deficiency of liver and kidney and syndrome of upper hyperactivity of liver yang.
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