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Analysis of risk factors in patients with polycystic ovary syndrome of reproductive age in Wenzhou Hospital of Traditional Chinese Medicine |
YING Haiqiong ZHU Xiaoli JI Shuangshuang XU Jing HU Xinxin |
Department of Gynecology of Traditional Chinese Medicine, Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang Province, Wenzhou 325000, China |
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Abstract Objective To investigate the risk factors in patients with polycystic ovary syndrome of reproductive age in Wenzhou Hospital of Traditional Chinese Medicine. Methods A total of 1 530 medical examiners of childbearing age who were examined in Wenzhou Hospital of Traditional Chinese Medicine from May 2019 to February 2021 were selected for the study, and the detection rate of polycystic ovary syndrome was counted and the risk factors for the occurrence of polycystic ovary syndrome were analyzed. Results A total of 1 530 questionnaires were sent out in this survey and 1 300 were returned, with a return rate of 84.80%. The detection rate of polycystic ovary syndrome in 1 300 persons of reproductive age was 38.46%. Univariate analysis showed that the occurrence of polycystic ovary syndrome in reproductive age was associated with age, body mass index, family history of hypertension, family history of obesity, time taken from menarche to regular menstruation, hirsutism, and acne, with statistically significant differences (P < 0.05). Logistic regression analysis showed that age 18 -< 26 years, body mass index ≥25 kg/m2, family history of hypertension, family history of obesity, time taken from menarche to regular menstruation >2 years, hirsute F-G ≥6 points, and acne >10 were risk factors for the formation of polycystic ovary syndrome of the reproductive age (OR > 1, P < 0.05). Conclusion The development of polycystic ovary syndrome in reproductive age is mainly influenced by age, body mass index, family history of hypertension, hirsutism, family history of obesity, time taken from menarche to regular menstruation, acne, and other factors. Effective prevention of risk factors can reduce the occurrence of polycystic ovary syndrome.
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[1] Osibogun O,Ogunmoroti O,Michos ED. Polycystic ovary syndrome and cardiometabolic risk:Opportunities for cardiovascular disease prevention [J]. Trends Cardiovasc Med,2020, 30(7):399-404.
[2] Ganie MA,Vasudevan V,Wani IA,et al. Epidemiology,pathogenesis,genetics & management of polycystic ovary syndrome in India [J]. Indian J Med Res,2019,150(4):333-344.
[3] 李晓玥,程军,白昕予,等.中药汤剂对多囊卵巢综合征闭经患者的中医证候疗效及月经周期、性激素水平的影响[J].中国基层医药,2021,28(12):1793-1797.
[4] 方群英,吴丽敏,孙秀英,等.不同中医证候多囊卵巢综合征不孕患者促排加指导同房临床特征和妊娠结局比较[J].中华中医药学刊,2019,37(11):2662-2666.
[5] 王峥,潘晓蕾,刘昭阳,等.多囊卵巢综合征中医证型与性激素、卵巢体积相关性研究[J].中国中医基础医学杂志,2019,25(4):490-492,534.
[6] 张春玲,刘志杰.补肾调经汤多方分段给药对多囊卵巢综合征患者促排卵结局、症状及性激素水平的影响[J].世界中医药,2019,14(4):970-973.
[7] 张美微,侯丽辉,李妍,等.痰湿证多囊卵巢综合征患者甲状腺激素水平与胰岛素抵抗的相关性研究[J].现代中西医结合杂志,2019,28(11):1146-1149,1231.
[8] 潘紫萌,侯丽辉,李妍,等.AMH水平与不同证型多囊卵巢综合征各临床指标的差异及相关性分析[J].医学研究杂志,2019,48(8):74-79.
[9] 中华医学会妇产科学分会内分泌学组,指南专家组.多囊卵巢综合征中国诊疗指南[J].中华妇产科杂志,2018, 53(1):2-6.
[10] 国家技术监督局.中华人民共和国国家标准中医临床诊疗术语:证候部分[S].北京:中国标准出版社,1997,39(7):28-32.
[11] 张红阳,侯丽辉,李妍,等.多囊卵巢综合征患者胰岛素抵抗与中医体质的相关研究[J].现代中西医结合杂志,2019,28(26):2851-2854.
[12] 张燕妮,刘雪维,秦海英,等.葛根素注射液辅助治疗多囊卵巢综合征不孕对性激素、胰岛素抵抗及抗氧化能力的影响[J].中国计划生育学杂志,2021,29(11):2292-2296.
[13] 李佩,穆丹,陈利平,等.多囊卵巢综合征患者血清SOX9 mRNA、PPARγ mRNA表达与疾病严重程度及预后的关系[J].国际检验医学杂志,2022,43(5):591-595,600.
[14] 张红阳,侯丽辉,孙淼.多囊卵巢综合征患者西医亚型与中医证型的相关研究[J].现代中西医结合杂志,2019, 28(17):1829-1833.
[15] 王宇,刘学奎,谢梁震,等.多囊卵巢综合征不同中医证型不孕症患者基线特征分析[J].中华中医药杂志,2021, 36(7):4318-4324.
[16] 郝星,白剑,任武,等.多囊卵巢综合征患者血清中内皮素-1、血管生成素样蛋白2与卵巢间质血流的关系[J].中国性科学,2022,31(2):44-49.
[17] 安旭琢,李晓莉.二甲双胍联合炔雌醇环丙孕酮片治疗多囊卵巢综合征患者对IGFB P-1、IL-18、抗氧化指标的影响[J].医学临床研究,2022,39(1):150-152.
[18] Chen Z,Liu L,Xi X,et al. Aberrant H19 Expression Disrupts Ovarian Cyp17 and Testosterone Production and Is Associated with Polycystic Ovary Syndrome in Women [J]. Reprod Sci,2022,29(4):1357-1367.
[19] 夏宛廷,黄晨曦,黄金珠,等.多囊卵巢综合征患者与饮食、运动、睡眠及情绪因素的相关性分析[J].中华中医药杂志,2020,35(12):6337-6340.
[20] 张帅,吴佩蔚,黄亚哲,等.中医辨证分型论治多囊卵巢综合征的疗效及其影响因素分析[J].世界中西医结合杂志,2021,16(2):363-366,371.
[21] 牛蔚,任健,田琪,等.多囊卵巢综合征中医证型分类及其关联理化指标的研究[J].山东中医杂志,2021,40(7):687-691.
[22] 张黎锐,郑薇,刘程,等.多囊卵巢综合征孕妇妊娠期增重模式与母儿结局的关系[J].首都医科大学学报,2021, 42(2):169-176.
[23] 宋琳奕,俞瑾,俞超芹.多囊卵巢综合征颗粒细胞线粒体功能障碍的研究进展[J].解放军医学杂志,2021,46(7):718-723.
[24] 冯路,宋雪阳,许朝霞,等.多囊卵巢综合征痰湿证的研究进展[J].天津中医药,2021,38(2):267-272.
[25] 晋娜,徐文秀,李长香,等.从标本论治多囊卵巢综合征经验[J].环球中医药,2021,14(4):700-703.
[26] 陈欢,刘秀,葛红山.维生素D与多囊卵巢综合征关系的研究进展[J].中国医学创新,2022,19(20):170-174.
[27] 陈运春,黄旴宁,孔嫦瑛,等.Inv(20)伴不孕症和多囊卵巢综合征一家系[J].中华检验医学杂志,2021,44(9):855-859. |
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