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Investigation and research on clinical characteristics, diagnosis, and treatment status of chronic heart failure patients in tertiary and first-class hospitals in Xinjiang area |
Refukaiti Abuduhalike Kailibinuer Abuduhalike SUN Juan Ailiman Mahemuti |
Department of Heart Failure, the First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830000, China |
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Abstract Objective To investigate the demographic data, clinical characteristics, and management of inpatients with chronic heart failure (CHF) in a tertiary hospital in Xinjiang. Methods This study was a cross-sectional study. From January 2018 to September 2020, 1 500 patients with CHF who were continuously hospitalized in the provincial tertiary hospitals in Xinjiang (the First Affiliated Hospital of Xinjiang Medical University, the People’s Hospital of Xinjiang Uygur Autonomous Region, and the Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region) and three municipal tertiary hospitals (the Second People’s Hospital of Kashgar, Yili Prefecture People’s Hospital, Changji Prefecture Traditional Chinese Medicine Hospital) were selected. The general information, risk factors, etiology of CHF, examination results, drug use, and other clinical data of the selected patients were collected. Results A total of 1 451 CHF patients were finally included, including 967 males; the age was (64.14±13.13) years; the median hospital stay was nine days. Patients with CHF with reduced ejection fraction (HFrEF) and class Ⅲ cardiac function accounted for the highest proportions. The rates of ACEI/ ARB/ARNI, β-blocker, and aldosterone receptor antagonist use in HFrEF patients were 87.2%, 89.5%, and 88.0%, respectively. The proportion of CHF patients hospitalized in provincial tertiary hospitals was higher than that of municipal tertiary hospitals, while the length of stay was shorter than that of century tertiary hospitals, and the differences were statistically significant (P < 0.05). The rate of NT-Pro BNP/BNP examination in CHF patients in provincial tertiary hospitals, patients with HFrEF and cardiac function grade Ⅳ, patients undergoing pacing intervention, coronary intervention or bypass, and the proportion of hyperuricemia, anemia, and renal insufficiency in provincial tertiary hospitals were higher in the municipal tertiary hospital (P < 0.05). The proportion of HFrEF patients in provincial tertiary hospitals were higher than that of municipal tertiary hospitals; the proportion of patients using aldosterone receptor antagonists was lower than that of municipal tertiary hospitals (P < 0.05). Conclusion Coronary heart disease is the main cause of inpatient CHF in the top three hospitals in Xinjiang. CHF patients hospitalized in provincial tertiary hospitals were older and had worse cardiac function. There was no significant difference in the proportion of standardized drug use recommended by the guidelines for HFrEF patients hospitalized in provincial and municipal tertiary hospitals.
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