|
|
Research progress on regulation of psoriasis related immune cells by traditional Chinese medicine |
ZHAO Jiusi1 YANG Suqing2 ZHANG Qing2 |
1.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Department of Dermatology, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China |
|
|
Abstract Psoriasis, as a common chronic inflammatory disease in dermatology, has the characteristics of long duration and easy to recurrence. The traditional western medicine treatment effect is not good and the side effect is great. Traditional Chinese medicine treatment can not only treat the symptoms and root causes, effectively improve skin lesions, but also regulate the imbalance of the body’s internal environment. This review combined with the latest research, the traditional Chinese medicine treatment to improve under the abnormal state of T lymphocyte subsets, horniness cells, dendritic cells, mast cells, macrophages, and inhibition of peripheral blood related inflammatory cytokine secretion were systematically stated, provide theoretical basis for multiple targets for treatment of Chinese medicine psoriasis, in order to more accurately guide to clinical practice.
|
|
|
|
|
[1] 黄丹,陈崑.银屑病相关流行病学调查进展[J].诊断学理论与实践,2021,20(1):48-52.
[2] Rendon A,Sch?覿kel K. Psoriasis Pathogenesis and Treatment [J]. IntJ Mol Sci,2019,20(6):1475.
[3] 陈洁,曹筱筱,徐蓉,等.银屑病血热及血瘀证患者外周血Th1/Th2细胞表达差异研究[J].中国中西医结合杂志,2014,34(1):46-50.
[4] 周莹,戴迭勤,李健哲,等.爽肤汤治疗老年寻常性银屑病疗效及对外周血TH1/TH2平衡的影响[J].辽宁中医杂志,2022,49(4):127-130.
[5] 李红岩,牟兆新,侯振江.Th17细胞及其分泌的细胞因子在自身免疫性疾病中的研究进展[J].医学综述,2021,27(14):2749-2754.
[6] 陈旭娥,刘志香,吴艳,等.寻常型银屑病皮损中Th17细胞相关因子的表达[J].中国麻风皮肤病杂志,2008,24(3):176-178.
[7] 刘秀玲,付雪梅,郑成彬.窄谱中波紫外线配合活血解毒方对血瘀型银屑病患者血液流变学及血清Th1/Th2细胞因子和IL-17表达的影响[J].中国美容医学,2022,31(1):102-107.
[8] 马维江,杨立民,张利,等.Th22细胞和白细胞介素-22的生物学作用及在结核病免疫中作用的研究进展[J].感染、炎症、修复,2019,20(3):189-192.
[9] 李志,杨婷婷,李文哲.特应性皮炎患者外周血中Th22、Treg细胞及其细胞因子表达的研究[J].中国实验诊断学,2019,23(5):788-791.
[10] 张丽明,段姚尧,董小青,等.Th22细胞及其效应因子IL-22与炎症性皮肤病关系的研究进展[J].中国药理学通报,2014,30(7):905-907.
[11] 陈安婧.Th9、Th22细胞在复发型寻常型银屑病(血热证)中的表达特点与加味凉血消风散对其的调控作用[D]. 成都:成都中医药大学,2020.
[12] 王傲,王英,李思彤,等.滤泡辅助性T细胞及其在银屑病中的研究进展[J].中国中西医结合皮肤性病学杂志,2020,19(4):384-387.
[13] 安月鹏,杨素清,刘畅.蜈蚣败毒饮对银屑病小鼠滤泡辅助性T细胞相关因子STAT3、PD-1表达的影响[J].中国中医药信息杂志,2022,29(6):55-61.
[14] Toda A,Piccirillo CA. Development and function of naturally occurring CD4+CD25+ regulatory T cells [J]. J Leukoc Biol,2006,80(3):458-470.
[15] 曹爽,周妍妍,杨素清,等.中医药干预银屑病Th17/Treg平衡的研究进展[J].中国实验方剂学杂志,2021,27(19):225-232.
[16] 庄洪建,庄烁.凉血消银汤对进行期寻常型银屑病Th17相关细胞因子的调节作用研究[J].中国实用医药,2021, 16(24):1-5.
[17] 黄海勇,黄功华,刘新光.角质形成细胞在银屑病中作用的研究进展[J].中国免疫学杂志,2020,36(12):1527- 1530.
[18] 刘宇,赵京霞,王燕,等.养血解毒方对银屑病角质形成细胞紧密连接的调节作用[J].中国实验方剂学杂志,2020,26(3):62-70.
[19] 曹志强,张春红.树突状细胞在银屑病中的研究进展[J].中国麻风皮肤病杂志,2021,37(12):813-816.
[20] 沈肖俐.寻常性银屑病患者外周血干扰素γ和肿瘤坏死因子α及其受体mRNA的测定[J].国际免疫学杂志,2015,38(4):336-339.
[21] 王明星,王燕,赵京霞,等.树突状细胞在咪喹莫特诱导的银屑病样小鼠模型中的表达及凉血解毒方的干预作用[J].首都医科大学学报,2017,38(2):249-259.
[22] 安阳,刘辰晓,陈广洁.肥大细胞在类风湿关节炎中作用的研究进展[J].现代免疫学,2021,41(5):431-435.
[23] 贺学荣,何川,龚建平.肥大细胞激活机制与变态反应性疾病关系的研究进展[J].重庆医学,2014,43(9):1139-1141.
[24] 刘晋华,尤光甫,李玉萍.青黛克银丸治疗银屑病抗瘙痒作用机制的研究[J].华西药学杂志,2011,26(4):342-344.
[25] 陈建霞,冯燕艳.巨噬细胞在银屑病发病机制中作用的研究进展[J].临床皮肤科杂志,2019,48(11):714-716.
[26] Qie C,Jiang J,Liu W,et al. Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/-murine psoriasis [J]. Theranostics,2020,10(23):10483-10497.
[27] 秦涛,何丽娜.芩珠凉血方配合NB-UVB治疗寻常型银屑病血热证疗效及对其T淋巴细胞亚群和MCP-1、M-CSF水平的影响[J].中国中西医结合皮肤性病学杂志,2019,18(2):127-131.
[28] Chang SH,Dong C. Signaling of interleukin-17 family cytokines in immunity and inflammation [J]. Cell Signal,2011,23(7):1069-1075.
[29] Johnston A,Fritz Y,Dawes SM,et al. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation [J]. J Immunol,2013,190(5):2252-2262.
[30] 解欣然,张蕾,刘欣,等.紫草素对IL-17诱导角质形成细胞增殖及趋化因子表达的影响[J].中国中药杂志,2015,40(5):946-949.
[31] 李玥熠,赵润生,郑书深. IL-22在银屑病发病机制中的研究进展[J].中国免疫学杂志,2021,37(9):1149- 1154.
[32] Zenewicz LA. IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 Biology [J]. Front Immunol,2021,12:766586.
[33] 贾红侠,何焱玲,兰东,等.姜黄汤剂在治疗寻常型银屑病中的辅助价值及其对血清IL-22水平的影响[J].中国美容医学,2021,30(11):107-110.
[34] Goodman WA,Levine AD, Massari JV,et al. IL-6 signaling in psoriasis prevents immune suppression by regulatory T cells [J]. J Immunol,2009,183(5):3170-3176.
[35] 肖敏,徐洪来,吴栋杰,等.黄芩苷对泛发性脓疱型银屑病患者机体Th1/Th2失衡及T-bet/GAGA-3表达的影响[J].广西医学,2021,43(16):1972-1976,1992.
[36] 曹丽楠.凉血消银汤联合复方芩柏软膏对进行期银屑病患者的疗效及血清TNF-α、IL-1、IL-6的影响[J].世界中西医结合杂志,2018,13(12):1707-1710.
[37] 王亚莎,张敏,陈卫卫.消疕汤对银屑病患者外周血免疫细胞平衡及NF-κB、Lp-PLA2的影响[J].中医药信息,2021,38(11):66-70. |
|
|
|