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| Clinical effect of acupuncture assisted Citalopram Hydrobromide in the treatment of elderly patients with post-stroke insomnia and depression |
| ZHOU Xueping CAO Lijuan YAN Pingkang |
Department of Geriatrics, Jinhua Second Hospital, Zhejiang Province, Jinhua 321016, China
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Abstract Objective To explore the clinical effect of acupuncture assisted Citalopram Hydrobromide in the treatment of elderly patients with post-stroke insomnia and depression. Methods A total of 78 elderly patients with post-stroke insomnia and depression admitted to Jinhua Second Hospital, Zhejiang Province from May 2019 to June 2021 were selected and divided into control group (Citalopram Hydrobromide Tablets) and experimental group (acupuncture assisted Citalopram Hydrobromide Tablets) by random number table method, with 39 cases in each group. After continuous treatment for four weeks, the efficacy of the two groups was evaluated. The depression grade, sleep quality, and serological indexes of the two groups before and after treatment were counted, and the incidence of adverse reactions in the two groups was recorded. Results The efficacy of the experimental group was better than that of the control group, and the difference was statistically significant (P ＜ 0.05). After treatment, the scores of Hamilton depression scale and Pittsburgh sleep quality index in the two groups were lower than those before treatment, and the experimental group was lower than the control group, and the differences were statistically significant (P ＜ 0.05). After treatment, the levels of 5-hydroxytryptamine and brain-derived neurotrophic factor in the two groups were higher than those before treatment, and the experimental group was higher than the control group, and the differences were statistically significant (P ＜ 0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion Acupuncture assisted Citalopram Hydrobromate has a definite effect on elderly patients with insomnia and depression after stroke, which can improve the sleep disorder and depression tendency of patients, with good safety, and can be applied in clinical practice.
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