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Diagnosis value of high frequency ultrasound, real-time shear wave elastography, and color Doppler flow imaging in benign and malignant BI-RADS 4 breast masses |
LIU Haihua XIA Qun CHENG Yangmei XIE Hongjuan HU Jinhua▲ |
Department of Ultrasound, Anqing First People’s Hospital of Anhui Province, Anhui Province, Anqing 246000, China |
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Abstract Objective To research the the value of high frequency ultrasound, real-time shear wave elastography (SWE), and color Doppler flow imaging (CDFI) in the diagnosis of benign and malignant BI-RADS 4 breast masses. Methods A total of 80 patients with breast masses treated in Anqing First People’s Hospital of Anhui Province from September 2020 to September 2021 were selected as the research objects. They were divided into benign group (53 cases) and malignant group (27 cases) according to surgical pathology result or biopsy result. All patients completed high-frequency ultrasound, SWE, and CDFI before operation or one week before pathological biopsy. SWE parameters and CDFI blood flow grade of different breast masses were compared. Receiver operating characteristic curve was drawn to analyze the diagnostic value of high-frequency ultrasound, SWE, and CDFI alone and in combination in the diagnosis of malignant breast masses. Results The maximum value of elastic modulus, the mean value of elastic modulus, the ratio of breast mass to the mean value of low fat elasticity in the same layer, and the variance value of elastic modulus in malignant group were higher than those in benign group (P < 0.05). The difference of CDFI blood flow grade between two groups was statistically significant (P < 0.05). The area under the curve, sensitivity, and specificity of combined examination were higher than those of individual tests. Conclusion High frequency ultrasound, SWE, and CDFI can provide imaging data for the clinical diagnosis of breast masses from multiple angles, and the combination examination can accurately identify the pathological nature of BI-RADS 4 breast masses, which is worthy of active promotion in clinic.
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