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Early screening value of optical coherence tomography angiography for retinal microcirculation disorders in patients with diabetic retinopathy |
XIA Ying1 SHI Mei1 ZHANG Ming2▲ |
1.Department of Ophthalmology, Wuxi No.5 People’s Hospital, Jiangsu Province, Wuxi 214007, China;
2.Department of Ophthalmology, Xuzhou No.1 People’s Hospital, Jiangsu Province, Xuzhou 221000, China |
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Abstract Objective To explore the early screening value of optical coherence tomography angiography(OCTA) for retinal microcirculation disorders in patients with diabetic retinopathy (DR). Methods A total of 125 DR patients admitted to Wuxi No.5 People’s Hospital from May 2018 to March 2021 were selected as the research objects. According to whether retinal microcirculation disorder occurred, they were divided into occurrence group (67 cases) and non-occurrence group (58 cases). All patients received fluorescein fundus angiography (FFA) and OCTA screening within three days of admission. The deep retinal macular vascular density (MVD), chorioretinal MVD, superficial retinal MVD, and the area of the foveal avascular zone (FAZ) were compared between two groups; the results of FFA screening were used as the gold standard to analyze the screening value of OCTA for retinal microcirculation disorders in DR patients. Results The deep retinal MVD, superficial retinal MVD, and chorioretinal MVD in occurrence group were lower than those in non-occurrence group, and the area of FAZ was higher than that in non-occurrence group (P < 0.05). The sensitivity and specificity of OCTA for screening retinal microcirculation disorders in DR patients were 95.52% and 91.38%, Kappa=0.873, indicating good consistency. Conclusion OCTA has a good value in early screening of retinal microcirculation disorders in DR patients and can be further promoted.
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