超声造影对颈动脉粥样硬化斑块稳定性及新生血管的评估价值研究

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Abstract Objective To explore the evaluation value and clinical significance of contrast-enhanced ultrasonography on the stability of carotid atherosclerotic plaque and new blood vessels. Methods From July to October 2017, 200 patients taken the carotid artery ultrasonography examination in Pudong New Area People′s Hospital of Shanghai City were selected. The relationship between carotid artery atherosclerotic plaque, plaque thickness and plaque enhancement were statistically analyzed. Patients with internal carotid artery stenosis were divided into two groups: symptomatic group (n = 74) and asymptomatic group (n = 126), according to whether there were cerebral infarction and transient ischemic attack. The intensity of plaque contrast enhancement (EI), the ratio of the plaques(ratio), and plaque enhancement in the plaques were calculated respectively. Results The plaque echo was low echo and mixed echo, and the ratio of plaque enhancement were significantly higher than that of medium echo and strong echo, and the differences were statistically significant (P < 0.05). Contrast-enhanced ultrasound enhancement ratio of plaque of thickness more than 2.0 mm were significantly higher than that of the thickness of 2.0 mm or less plaques, the difference was statistically significant (P < 0.05). In patients with degree of internal carotid artery stenosis ≥50% (n = 91), the symptom group EI and ratio were significantly higher than the asymptomatic group, the composition of grade 1 plaque enhancement in the symptomatic group was significantly lower than that in the asymptomatic group, and the composition of the grade 3 plaques enhancement was significantly higher than that in the asymptomatic group, the differences were statistically significant (P < 0.01). Conclusion Contrast-enhanced ultrasonography can show the angiogenesis in the plaques, and the enhancement degree of plaque is closely related to the echo, thickness. There is a close relationship between atherosclerotic plaque property, vascular grading in plaques, cerebral infarction, cerebral ischemia and other clinical symptoms.

Key words： Color doppler ultrasound Contrast-enhanced ultrasonography Atherosclerosis New vessels

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	ZHANG Yuan DENG Shuhao ZHU Yicheng JIANG Quan

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ZHANG Yuan DENG Shuhao ZHU Yicheng JIANG Quan. Study of the evaluation value of contrast-enhanced ultrasonography on the stability of carotid atherosclerotic plaque and new blood vessels[J]. 中国医药导报, 2018, 15(28): 142-145.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I28/142

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