非肌层浸润性膀胱癌术后尿路感染病原学及其影响因素分析

doi:10.20047/j.issn1673-7210.2022.27.16

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Abstract Objective To investigate the pathogenic bacteria detected and the influencing factors of urinary tract infection (UTI) in patients with non-muscle invasive bladder cancer (NMIBC) after transurethral resection of bladder tumor (TURBT), to provide an important basis for clinical prevention and integrated treatment of traditional Chinese and western medicine. Methods The clinical data of 318 patients with NMIBC treated by TURBT in Hubei Provincial Hospital of Traditional Chinese Medicine from January 2011 to December 2020 were retrospectively investigated. The distribution characteristics of pathogenic bacteria in patients with UTI were observed, and the influencing factors of postoperative UTI were analyzed by logistic regression. Results UTI occurred in 38 of 318 patients, and the infection rate was 11.95%; 51 strains of pathogenic bacteria were detected in 38 UTI patients, among which 35 strains of Gram negative bacilli accounted for 68.63%, and 13 strains of Gram positive coccus accounted for 25.49%, three strains of fungus accounted for 5.88%. There were significant differences in age, tumor site, diabetes, hypertension, postoperative indwelling catheter, spleen and kidney deficiency syndrome between the two groups (P ＜ 0.05). Age ≥65 years, multiple tumor sites, diabetes mellitus, hypertension, postoperative induration catheter ≥7 days, and spleen and kidney deficiency syndrome type were independent risk factors for postoperative UTI (OR ＞ 1，P ＜ 0.05). Conclusion Patients after TURBT with high probability of postoperative UTI, the influencing factors are complex, and effective clinical intervention measures of integrated traditional Chinese and western medicine should be proposed based on the distribution and influencing factors of pathogenic bacteria to improve the prognosis of patients.

Key words： Non-muscular invasive bladder cancer Transurethral resection of bladder tumor Urinary tract infection Pathogenic bacteria Risk factors

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	YNAG Liu1 NI Wei2 PENG Li1

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YNAG Liu1 NI Wei2 PENG Li1. Analysis of etiology and risk factors of postoperative urinary tract infection for non-muscular invasive bladder cancer[J]. 中国医药导报, 2022, 19(27): 72-75.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.27.16 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I27/72

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