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Study on the medication rules of facial mask prescription of traditional Chinese medicine for acne based on association rules |
PEI Yue1 LIANG Haiying2 ZENG Jianbo1 PING Ruiyue1 LI Hongyi2 |
1.The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510095, China;
2.Department of Dermatology, Guangdong Hospital of Traditional Chinese Medicine, Guangdong Province, Guangzhou 510120, China |
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Abstract Objective To analyze the medication rules of facial mask prescription of traditional Chinese medicine for acne. Methods The Chinese medicine prescriptions containing facial mask prescription of traditional Chinese medicine for acne were researched from CNKI, Wanfang, VIP, CBM from January 2012 to March 2018, and the frequency of each prescription, four nature of drugs, five flavors, channel tropism, classification and the association rules between drugs were extracted and analyzed by TCMISS Chinese medicine inheritance assistant platform. Results Two hundred and fifty-one Chinese herbal prescriptions were collected. The high frequency herbs were Radix et Rhizoma Rhei, Radix Salviae Miltiorrhizae, Angelicae Dahuricae, Radix Scutellariae, Flos Lonicerae, Cortex Phellodendri, Fructus Forsythiae, Herba Taraxaci, Rhizoma Coptidis, Flos Chrysanthemi Indici, Radix Sophorae Flavescentis, and so on. The key drug combinations were “Radix et Rhizoma Rhei, Angelicae Dahuricae”, “Radix et Rhizoma Rhei, Radix Salviae Miltiorrhizae”, “Radix et Rhizoma Rhei, Radix Scutellariae”. The distribution of four nature of drugs was mainly cold, cool, warm, calm; the distribution of five flavors was mainly bitter, pungent, sweet, tasteless; the distribution of the channel tropism was mainly liver, stomach, heart, lung, spleen channel. Conclusion The facial mask prescription for external use of acne takes “clearing heat and activating blood” as the main treatment method, and the core drug is mainly for clearing heat; prescription drugs maimly take “clearing heat and removing toxicity, promoting blood circulation for removing blood stasis” as principle.
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Fund:国家中医药管理局中医药行业科研专项项目(201507003)。 |
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[1] 杨菲,刘涛峰.中医外治法治疗痤疮的研究进展[J].中医药临床杂志,2017,29(3):433-435.
[2] 孙欣荣,刘志宏,黄爱文,等.痤疮发病机制及其药物治疗的研究进展[J].中国药房,2017,28(20):2868-2871.
[3] Vos T,Flaxman AD,Naghavi M,et al. Years lived with disability(YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010:a systematic analysis forthe Global Burden of Disease Study 2010 [J]. Lancet,2012,380(9859):2163-2196.
[4] 裴香萍,张淑蓉.高效液相色谱法测定安肺胶囊中黄芩苷的含量[J].世界中西医结合杂志,2010,5(1):40.
[5] 宋佳兴,张鹏宇,杜雅琦.中医外治法治疗痤疮的临床进展[J].世界最新医学信息文摘,2017,17(A2):86-87.
[6] 肖静秋,冯大鹏,王永慧,等.中药外用治疗寻常型痤疮研究进展[J].新中医,2017,49(10):146-148.
[7] 范瑛,宋坪.自拟中药面膜治疗痤疮后红斑及色素沉着临床疗效观察[J].中国中西医结合皮肤性病学杂志,2013, 12(5):281-284.
[8] 张向红,程黎晖.大黄的药理作用及临床应用研究进展[J].中国药业,2009,18(21):76-78.
[9] 臧镭镭,宋月晗,吴凤芝,等.从皮损症状特点与分布辨治痤疮[J].环球中医药,2016,9(7):814-816.
[10] 安维新,张正华.中药茶饮结合耳穴治疗中学生痤疮120例疗效观察[J].西部中医药,2016,29(5):101-103.
[11] 陈燕.痤疮的中医辨治总结[J].光明中医,2013,28(1):155-157.
[12] 殷红武,张理梅.中医辨证分型配合火针治疗痤疮的疗效观察[J].中国现代医生,2016,54(15):119-122.
[13] 卢富琼,余珍,杨帆,等.果酸换肤联合阿达帕林凝胶外用治疗轻中度痤疮的效果观察[J].中国当代医药,2016, 23(35):37-39.
[14] 乔立新,熊芬霞,李红梅.单味大黄治疗寻常痤疮的临床观察[J].中国煤炭工业医学杂志,2005,8(9):1032.
[15] 方雪琴.黄连解毒汤药理作用研究进展[J].中成药,2015, 37(10):2254-2259.
[16] 杨秀荣.自拟黄连解毒汤治疗慢性盆腔炎30例[J].黑龙江中医药,2010,39(2):13.
[17] 糜澜.黄连解毒汤化裁治疗宫颈糜烂38例[J].实用中医药杂志,2002(11):42.
[18] 李运伦.黄连解毒汤加减治疗高血压病30例临床研究[J].国医论坛,2000(2):38-39.
[19] 尹承芬,龚平,姚咏明.脓毒症时调节性T细胞作用机制的研究进展[J].感染、炎症、修复,2013,14(1):50-53.
[20] 贺大智,马建伟.论阳郁寒凝型痤疮的治疗[J].环球中医药,2017,10(7):730-731.
[21] 季宇彬.中药有效成分药理与应用[M].哈尔滨:黑龙江科技出版社,1994:456,527-528.
[22] 吴媛媛,蒋桂华,马逾英,等.白芷的药理作用研究进展[J].时珍国医国药,2009,20(3):625-627.
[23] 郭四红.白芷痤康散外敷治疗痤疮47例疗效观察[J].河南职工医学院学报,2005,17(1):41-42.
[24] 周淑敏.白芷香豆素的提取及其抑菌活性研究[J].食品工业,2014,35(3):141-144.
[25] 林峥嵘,周文,游世芬,等.刺血加穴位注射治疗痤疮临床观察[J].西部中医药,2016,29(3):102-104.
[26] 林晓琼.加用自制中药倒膜治疗面部痤疮的临床疗效观察[J].中国现代医生,2017,55(12):91-94.
[27] 涂华中.重用白芷愈痤疮[J].中医杂志,2000,41(3):137-138. |
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