益气温阳方治疗脾气虚弱型持续性中重度变应性鼻炎的临床效果

doi:10.20047/j.issn1673-7210.2022.26.30

Abstract
Figure/Table
References (24)
Related Citation (15)

Download: PDF (565 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To observe the clinical effect of Yiqi Wenyang Decoction in the treatment of persistent moderate and severe allergic rhinitis (AR) of spleen qi weakness type. Methods One hundred and twenty-six patients with persistent moderate and severe AR treated in Jiangsu Province Hospital of Chinese Medicine from June 2020 to October 2021 were selected as the research objects. They were divided into control group and study group by envelope lottery, with 63 cases in each group. The control group was given routine treatment, and the study group was given Yiqi Wenyang Decoction on the basis of the control group, with 14 days as a course of treatment and two consecutive courses of treatment. The clinical efficacy, clinical symptoms and signs scores, serum cytokine levels and adverse reactions were compared between the two groups. Results The clinical efficacy of the study group was better than that of the control group, and the difference was statistically significant (P < 0.05). After treatment, the clinical symptoms, signs and total scores of the two groups were lower than those before treatment, and the study group was lower than the control group, the differences were statistically significant (P < 0.05). After treatment, the levels of interferon-γ (IFN-γ) and interleukin (IL)-1 in the two groups were higher than those before treatment, the levels of IL-13, IL-4, and IL-35 in the two groups were lower than those before treatment, and the levels of IFN-γ and IL-1 in the study group were higher than those in the control group, the levels of IL-13, IL-4, and IL-35 in the study group were lower than those in the control group, and the differences were statistically significant (P < 0.05). There were no obvious adverse reactions in both groups. Conclusion Yiqi Wenyang Decoction in the treatment of persistent moderate and severe allergic rhinitis AR patients can improve symptoms and reduce the level of inflammatory factors, with significant curative effect.

Key words： Yiqi Wenyang Decoction Spleen qi weakness syndrome Persistent moderate and severe allergic rhinitis Curative effect Adverse reaction

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CHEN Min LU Yawen SHI Jun

Cite this article:

CHEN Min LU Yawen SHI Jun. Clinical effect of Yiqi Wenyang Decoction in the treatment of persistent moderate and severe allergic rhinitis of spleen qi weakness type[J]. 中国医药导报, 2022, 19(26): 133-136.

URL:

https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.26.30 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I26/133

[1] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组，中华医学会耳鼻咽喉头颈外科学分会鼻科学组.中国变应性鼻炎诊断和治疗指南（2022年，修订版）[J].中华耳鼻咽喉头颈外科杂志，2022，57（2）：106-129.
[2] 马春，李淑玲，郝如彬，等.中医药治疗变应性鼻炎的作用机制及研究进展[J].中国中医基础医学杂志，2019，25（10）：1473-1476.
[3] 董博，金修桥.变应性鼻炎治疗的研究进展[J].医学综述，2021，27（1）：141-145.
[4] 王雅琦，赵蔚波，严云，等.246例变应性鼻炎患者的中医体质分布规律调查研究[J].天津中医药，2021，38（5）：572-576.
[5] 刘玉，严道南，王海丹，等.益气温阳方对变应性鼻炎患者血清细胞因子水平和免疫耐受功能的影响[J].中国中医急症，2020，29（10）：1763-1765，1780.
[6] 赵雪飞.益气温阳方治疗肺脾两虚型过敏性鼻炎的临床效果[J].临床合理用药杂志，2022，15（2）：132-134.
[7] 中华耳鼻咽喉头颈外科杂志编辑委员会，中华医学会耳鼻咽喉科分会.变应性鼻炎的诊治原则和推荐方案（2004年，兰州）[J].中华耳鼻咽喉头颈外科杂志，2005， 40（3）：166-167.
[8] 薛建国，岳沛平.中医病症诊疗标准与方剂选用[M].北京：人民卫生出版社，2001：732.
[9] 程雷，董震，孔维佳，等.变应性鼻炎诊断和治疗指南（2015年，天津）[J].中华耳鼻咽喉头颈外科杂志，2016， 51（1）：6-24.
[10] 秦岭，芦芸，陈剑，等.针刺联合益气温阳方治疗肺气虚寒型过敏性鼻炎疗效观察[J].河南中医，2021，41（8）：1247-1250.
[11] 赵亚娟，单立影，田海芳，等.益气温阳方对变应性鼻炎患者血清炎性反应及气道功能的影响[J].世界临床药物，2021，42（3）：172-176，187.
[12] 严芮雯，陈旭青，严道南.益气温阳方对变应性鼻炎小鼠NK细胞细胞因子分化影响的研究[J].中医药信息，2020，37（2）：29-32.
[13] 严道南.严道南效方治验——益气温阳方[J].江苏中医药，2021，53（8）：5-6.
[14] 刘尚耀，胡环宇，吴智深.孟鲁司特对变应性鼻炎大鼠Th1/Th2失衡的免疫调节作用研究[J].中国临床药理学杂志，2020，36（6）：674-677.
[15] 延青，杨花荣，王娜娜.变应性鼻炎患者miR-21表达与Th1/Th2平衡的关系[J].现代医学，2021，49（6）：641-645.
[16] 彭慧慧，冷建杭，沈俊娅，等.Th17/Treg和Th1/Th2细胞失衡对变应性鼻炎发病机制的研究[J].中国卫生检验杂志，2020，30（18）：2234-2237.
[17] 邓小刚，颜永江，潘建兵，等.血清白细胞介素细胞因子联合IgE在变应性鼻炎中的表达及临床诊断价值分析[J].中国卫生检验杂志，2021，31（2）：239-241，251.
[18] 蔡诗茹，娄鸿飞.变应性鼻炎的神经免疫调节机制[J].临床耳鼻咽喉头颈外科杂志，2021，35（9）：859-864.
[19] 胡燕，蒋惠珍，罗洁.升阳益肾汤联合氯雷他定治疗哮喘合并变应性鼻炎患儿的效果[J].中国医药导报，2020， 17（11）：80-83，97.
[20] 翟建金，刘向祎.变应性鼻炎中脂代谢异常与炎症反应的研究进展[J].标记免疫分析与临床，2021，28（11）：1985-1989.
[21] 潘佳创，刘男男，张艺，等.麻黄细辛附子汤治疗变应性鼻炎的中药复方科研思路[J].世界中医药，2021，16（18）：2784-2787.
[22] 卓小玉，陈晶，田明，等.麻黄的化学成分与药理作用研究进展[J].中医药信息，2021，38（2）：80-83.
[23] 帖晓燕，张云鹤，辛国雄，等.党参米炒炮制及其药理作用研究进展[J].中国中医药信息杂志，2021，28（4）：140-144，封3.
[24] 邢楠楠，屈怀东，任伟超，等.五味子主要化学成分及现代药理作用研究进展[J].中国实验方剂学杂志，2021， 27（15）：210-218.