|
|
Wei Ni’s experience abstract in treating gouty arthritis in young people |
CHEN Xia WEI Ni#br# |
Department of Rheumatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China |
|
|
Abstract Gout is a heterogeneous group of diseases caused by purine metabolism disorder and/or uric acid excretion disorder. Gouty arthritis is the main clinical manifestation. The prevalence of gouty arthritis is increasing year by year, showing a trend of younger onset. Associate chief physician Wei Ni thinks that compared with elderly patients, young patients with gouty arthritis have more congenital kidney qi deficiency and more frequent drinking and high-purine diets. In addition, bad emotions cause stagnation of liver qi, which affects the heart and lungs over time, and aggravates phlegm and dampness,blood stasis. These factors can cause frequent attacks of gouty arthritis, high blood uric acid levels, and a higher chance of tophi. Associate chief physician Wei Ni emphasizes that the five zang viscera should be coordinated to eliminate the source of phlegm, dampness, and blood stasis in the treatment of young patients with gouty arthritis. At the same time, the drug of dispelling stasis and removing obstruction in collaterals should be used as early as possible to prevent the formation of tophi.
|
|
|
|
|
[1] Dalbeth N,Choi HK,Joosten LAB,et al. Gout [J]. Nat Rev Dis Primers,2019,5(1):69.
[2] Key?覻er G. Gout arthritis: Pathogenesis, diagnostics and treatment[J]. Dtsch Med Wochenschr,2020,145(14):991-1005.
[3] 中华医学会内分泌学分会.中国高尿酸血症与痛风诊疗指南(2019)[J].中华内分泌代谢杂志,2020,36(1):1-13.
[4] Yu KH,Luo SF. Younger age of onset of gout in Taiwan [J]. Rheumatology (Oxford),2003,42(1):166-170.
[5] Chen-Xu M,Yokose C,Rai SK,et al. Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends:The National Health and Nutrition Examination Survey,2007-2016 [J]. Arthritis Rheumatol,2019, 71(6):991-999.
[6] 陈建春,张世俊,付强,等.历代痛风病名研究[J].亚太传统医药,2021,17(4):171-174.
[7] 陈琳,周静,马武开,等.中医治疗痛风性关节炎的研究进展[J].风湿病与关节炎,2020,9(5):73-76.
[8] 杨小又,张丽萍,李涛,等.浅谈“诸湿肿满,皆属于脾”对痛风的诊疗启示[J].风湿病与关节炎,2020,10(1):39-41.
[9] 段宇晨,黄慈波,曹素艳,等.早发痛风111例临床特点与饮食饮品认知度及用药依从性的病例对照研究[J].中华风湿病学杂志,2020,24(5):328-333.
[10] 王茜,朱小霞,邹和建.青少年高尿酸血症病因及发病机制研究进展[J].中华风湿病学杂志,2019,23(11):781-785.
[11] 陈莉惠,陈思,刘风静,等.早发痛风患者的临床特征及相关影响因素分析[J].中华内分泌代谢杂志,2020,36(9):767-772.
[12] 罗丹,董秋梅.痛风中医证型分布与相关因素关系的研究进展[J].风湿病与关节炎,2021,10(8):69-71.
[13] 邓超,李谦华,杨莉娟,等.痛风患者身体成分特征及其临床意义[J].中华内科杂志,2021,58(10):751-757.
[14] 卓越,周仲瑜,张艳佶,等.从肝论肥胖[J].辽宁中医杂,2019,46(8):1636-1638.
[15] 马伊雯,陈海冰.心理应激与高尿酸血症的相关性研究进展[J].中华风湿病学杂志,2019,23(4):280-283.
[16] 赵琪珩,王芳,臧金凤,等.中青年痛风患者自我管理能力现状及影响因素分析[J].中华现代护理杂志,2021,27(23):3134-3138.
[17] Gupta MK,Singh JA. Cardiovascular Disease in Gout and the Protective Effect of Treatments Including Urate-Lowering Therapy [J]. Drugs,2019,79(5):531-541.
[18] 谢铱子,全世建.阳虚络痹与痛风[J].上海中医药杂志,2018,52(6):59-61.
[19] 马利丹,刘甜,陈颖,等.青年痛风石患者临床特点及相关危险因素研究[J].中华风湿病学杂志,2021,25(9):590-596.
[20] 李振彪,马旭,杨静,等.白芍总苷治疗大鼠急性痛风性关节炎的作用及对血清IL-1β、IL-6、TNF-α的影响[J].新医学,2017,48(6):380-384.
[21] 刘冬恋,秦琴,杨婷,等.白芍总苷对高尿酸血症肾损害大鼠肾脏的保护作用[J].食品工业科技,2021,42(22):344-349.
[22] 陈旭,贾波.叶天士虫药搜络“飞者升,地行者降”治法探析[J].中药杂志,2019,60(1):85-87.
[23] 王星,薛宁,李洪雷,等.防己黄芪汤对高尿酸血症小鼠降尿酸及肾保护作用机制的研究[J].中国中药杂志,2020,45(21):5248-5255.
[24] 杨大兴,单延具,张欣亮,等.黄芪甲苷对尿酸钠诱导的大鼠急性痛风性关节炎的防治作用及炎性反应机制研究[J].河北医药,2020,42(15):2245-2249.
[25] 陈绍华,王沁筠,吴昌桂,等.当归拈痛汤治疗急性痛风性关节炎疗效和作用机制的小鼠实验研究[J].中医全科医学,2021,24(24):3116-3121,3128.
[26] 吴昊霖,蔡来燕,樊好飞,等.杜仲、大血藤、鸡血藤和桑黄四种中药提取物的抗痛风作用研究[J].海南医学院学报,2021,27(19):1451-1457.
[27] 韩晶雪,刘鹏,刘毓,等.基于网络药理学研究“丹参-姜黄”药对降尿酸作用机制[J].中华中医药学刊,2021,39(3):172-176,269-271. |
|
|
|