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Research progress of relationship between Vaspin and obstructive sleep apnea hypopnea syndrome |
ZHOU Fuming WU Haiying BAI Zhong |
Department of Otorhinolaryngology, the Second Affiliated Hospital of Kunming Medical University, Yunnan Province, Kunming 650101, China |
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Abstract Vaspin, a serine protease inhibitor-derived from visceral adipose tissue, has been recently identified as a novel adipokine, which closely related to glucose and lipid metabolism. It participates the process of inflammation and endothelial function impairament, correlated with oxidative stress, simultaneouly. Vaspin is closely related to the occurrence and development of obstructive sleep apnea. This article reviews the possible mechanisms between Vaspin and obstructive sleep apnea hypopnea syndrome. At the same time, the research direction and hot spot are discussed briefly.
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