基于互联网平台游戏的认知功能训练对不同类型老年轻度认知损害患者的干预效果

doi:10.20047/j.issn1673-7210.2022.26.18

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Abstract Objective To investigate the intervention effect and sustained effect of difficulty adaptive computer cognitive training based on internet platform games on different types in elderly patients with mild cognitive impairment (MCI). Methods From January 2019 to December 2020, 90 elderly patients with MCI were recruited from Liaoning Jinqiu Hospital, Liaoning Provincial People’s Hospital, the First Hospital of China Medical University, and Shengjing Hospital of China Medical University. They were divided into forgetting group (45 cases) and non-forgetting group (45 cases). Both groups were given difficulty adaptive computer cognitive training based on internet platform games, and the intervention lasted for eight weeks. The two groups received cognitive assessment before, at immediately after intervention, and three months after the intervention, and the differences of cognitive function related indicators were compared between the two groups. Results The total scores of Montreal cognitive assessment (MoCA) in the two groups at immediately after intervention were higher than those before intervention, and the total scores of MoCA in the non-forgetting group at three months after intervention were lower than those at immediately after intervention (P ＜ 0.05). The total score of auditory verbal learning test (AVLT), short-delay recall score, and recognition score in the non-forgetting group at immediately after intervention were higher than those before intervention, the short-delayed recall score, and recognition score at three months after intervention were higher than those before intervention, long-delayed recall score was lower than that at three months after trecdment, and the total AVLT score and long-delayed recall score at three months after intervention were lower than those at immediately after intervention (P ＜ 0.05). The long-delayed recall score and recognition score in the forgetting group at immediately after intervention were higher than those before intervention, and at three months after intervention were lower than those at immediately after intervention (P ＜ 0.05). The total AVLT score and long-delay recall score of the non-forgetting group before intervention were higher than those of the forgetting group at the same time, the total AVLT score and short-delay recall score at immediately after intervention were higher than those in the forgetting group at the same time, the short delayed recall score and recognition score at three months after intervention were higher than those in the forgetting group at the same time (P ＜ 0.05). The Stroop-B time in non-forgetting group at immediately after intervention was longer than that before intervention, and at three months after intervention was shorter than that at immediately after intervention, the Stroop-C time in both groups at three months after intervention was shorter than that at immediately after intervention (P ＜ 0.05). The shape trails test-A time in both groups at immediately after intervention and three months after intervention was shorter than that before intervention (P ＜ 0.05). The digital span test (DST) recite in reverse order scores of the two groups at three months after intervention were lower than those before intervention and immediately after intervention, and the DST recite in reverse order score of the forgetting group at immediately after intervention was higher than those before intervention (P ＜ 0.05). The DST recite in order score and recite in reverse order score in the non-forgetting group before intervention were higher than those in the forgetting group at the same time, and the DST recite in order score at immediately after intervention was lower than that in the forgetting group at the same time (P ＜ 0.05). Conclusion The short-term intervention effect of difficulty adaptive computer cognitive training on different types of elderly patients with MCI has been confirmed, but its durability and long-term benefits are still uncertain and need to be confirmed by further studies.

Key words： Difficulty adaptive computer cognitive training Internet platform games Mild cognitive impairment Non-forgetting type

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	ZHANG Wei LI Yanling▲

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ZHANG Wei LI Yanling▲. Intervention effect of cognitive function training based on internet platform games on different types of elderly patients with mild cognitive impairment[J]. 中国医药导报, 2022, 19(26): 79-85.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.26.18 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I26/79

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