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Predictive value of serum sTREM-1, MCP-1, and hs-CRP levels in restenosis after PCI in elderly patients with acute myocardial infarction |
TANG Ying HUANG Zehui JIANG Yu▲#br# |
Department of General Medicine, Wuxi Second People’s Hospital, Jiangsu Province, Wuxi 214000, China |
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Abstract Objective To investigate the predictive value of serum soluble triggering receptor expresses on myeloid cells-1 (sTREM-1), monocytogenic protein 1 (MCP-1), and hypersensitivity C reactive protein (hs-CRP) levels after percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction. Methods A total of 98 elderly patients with acute myocardial infarction admitted to Wuxi Second People’s Hospital of Jiangsu Province from March 2018 to March 2021 were selected. All subjects were followed up for six months. According to the incidence of restenosis, thy were divided into restenosis group and non-restenosis group. The risk factors of restenosis after PCI were analyzed; the receiver operating characteristic (ROC) curve was used to predict the diagnostic efficacy of different indicators for restenosis after PCI in elderly patients with acute myocardial infarction. Results Restenosis occurred in 11 of 98 patients, with an incidence of 11.22%. The levels of sTREM-1, MCP-1, and hs-CRP in restenosis group were higher than those in non-restenosis group (P < 0.05). sTREM-1, MCP-1, and hs-CRP were risk factors for restenosis after PCI in elderly patients with acute myocardial infarction (OR = 3.770, 5.376, 6.241, P < 0.05). The area under the curve of sTREM-1, MCP-1, and hs-CRP combined in predicting restenosis after PCI in elderly patients with acute myocardial infarction was higher than that predicted by each index alone (P < 0.05). Conclusion Serum sTREM-1, MCP-1, and hs-CRP are all associated with restenosis after PCI in elderly patients with acute myocardial infarction, and the predictive efficacy of the combination test is better.
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[1] 张济,李光泽,俞慎林.血清高迁移率族蛋白B1、髓系细胞触发受体1对下肢动脉硬化闭塞症病人介入治疗后再狭窄的预测价值[J].临床外科杂志,2021,29(6):573-576.
[2] 王艺璇,宋琼,颜琬华.衰弱评估在预测老年急性心肌梗死患者冠状动脉介入术后再发心肌梗死中的作用[J].护士进修杂志,2021,36(8):673-676.
[3] 王韦,汪自龙.血浆同型半胱氨酸与高血压合并急性心肌梗死患者PCI术后发生支架内再狭窄的相关性分析[J].医学临床研究,2019,36(4):754-756.
[4] 苏黎,吴杰,柳竞谕.胸痹汤联合八段锦对老年急性心肌梗死患者心脏介入术后心肌修复及康复的影响[J].中医药导报,2021,27(12):97-102.
[5] 刘利萍,吴辉,宋翠梅.通阳宽胸方联合替格瑞洛对经皮冠状动脉介入术后老年急性心肌梗死患者心肌血流微循环及血小板功能的影响[J].中国民间疗法,2021,29(20):69-71.
[6] 周欣峰,戚韶红,周俊文,等.血清sTREM-1对下肢动脉硬化闭塞症支架植入术后血管再狭窄的预测价值[J].山东医药,2020,60(10):18-22.
[7] 胡法国,张莹,马翔宇.经皮冠状动脉介入治疗对老年急性心肌梗死患者心血管事件的影响及相关因素研究[J].中国临床医生杂志,2020,48(2):167-170.
[8] 马强,王慰敏,庞宏刚,等.血清可溶性髓系细胞触发受体1水平与下肢动脉硬化闭塞症患者支架植入术后再狭窄的关系研究[J].实用心脑肺血管病杂志,2019,27(2):38-42.
[9] 黄永翔,方快发,张亦辉,等.麝香保心丸对急性心肌梗死PCI术后患者中医证候疗效及支架内再狭窄影响[J].世界中西医结合杂志,2019,14(2):227-231.
[10] 刘瑞东,王小丽,陈莉莉.血清MCP-1、OPG水平与急性心肌梗死患者PCI术后血管再狭窄的关系[J].山东医药,2019,59(1):67-69.
[11] 汪蛟龙,李枫,宁伟.急性心肌梗死患者血脂水平变化与PCI术后并发症及预后的相关性分析[J].医学临床研究,2019,36(4):710-712.
[12] 彭春莉.早期心脏康复训练对老年急性心肌梗死患者PCI术后康复效果、心功能及生活质量的影响[J].中外医学研究,2022,20(3):165-168.
[13] 吴杰.急性心肌梗死心电图诊断标准的变化及面临的问题[J].中国心脏起搏与心电生理杂志,2012,26(3):270-271.
[14] 王执兵,刘俊,陈少源,等.冠脉支架术后再狭窄血管重塑与脂联素、单核细胞趋化因子-1和内皮功能的相关性[J].南方医科大学学报,2010,30(4):912-914.
[15] 杨士雪.血清MCP-1联合血浆NT-proBNP预测急性心肌梗死PCI术后并发心力衰竭的价值探讨[J].安徽医药,2019,319(13):1331-1340.
[16] 程建新,王丽娜,王琳.抑郁情绪对急性心肌梗死患者PCI术后支架内再狭窄的影响[J].国际精神病学杂志,2020,47(6):1204-1206,1209.
[17] 方喜波,洪书新,刘培敏.sTREM-1对急性心肌梗死患者支架内再狭窄的预测价值[J].心脑血管病防治,2020, 20(3):273-276.
[18] 徐伟干,岑锦明,符岳,等.急性心肌梗死患者CYP2C19基因多态性分布及氯吡格雷治疗对PCI术后不良心血管事件和再狭窄的影响[J].临床急诊杂志,2020,21(4):304-307,311.
[19] 陈玺全,邓小军,段青松,等.血清MCP-1、OPG与急性心肌梗死患者PCI后再狭窄的关系[J].海南医学,2017, 28(24):3983-3985.
[20] 刘丽军,马燕霞,邵丽莉,等.冠状动脉介入治疗对冠心病血浆单核细胞趋化因子-1和白细胞介素-6水平的影响[J].心血管康复医学杂志,2013,22(2):146-149.
[21] 王亚欣,桑文凤,贾冠华.首发急性心肌梗死患者运动恐惧现状及影响因素分析[J].中国护理管理,2022,22(1):63-69.
[22] 黄秀清,刘保逸,孙亮,等.急性心肌梗死患者炎症因子C反应蛋白对单核细胞趋化蛋白-1表达的影响[J].中国心血管杂志,2018,16(3):211-213.
[23] 周艳,张克昌,涂秀.miR-133/208对老年急性心肌梗死患者预后的预测价值[J].中国实验诊断学,2022,26(2):248-251.
[24] 龚莉,林茜,董铭琦.急性心肌梗死患者疲劳发展轨迹的调查研究[J].中华护理杂志,2022,57(2):176-181.
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