基于数据挖掘探讨中药治疗紧张型头痛的临床用药规律

doi:10.20047/j.issn1673-7210.2022.26.01

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Abstract Objective To explore and discuss the clinical medication rules of traditional Chinese medicine in the treatment of tension-type headache. Methods The prescriptions of traditional Chinese medicine in the treatment of tension-type headache were retrieved and sorted from CNKI, Wanfang Data, VIP, China Biomedical Literature Service System, and PubMed. The retrieval time was from inception to January 2021. Excel 2013, SPSS Statistics 26.0, and SPSS Modeler 18.0 were used for analysis with the observation indexes of medication frequency, efficacy classification, nature and flavour, channel tropism, cluster analysis and association rules. Results A total of 157 prescriptions were included, containing 175 traditional Chinese medicines. There were 35 kinds of traditional Chinese medicine with medication frequency ≥15, most of which were Chuanxiong Rhizoma, Paeoniae Radix Alba, Glycyrrhizae Radix Et Rhizoma, Bupleuri Radix, Angelicae Sinensis Radix and Angelicae Dahuricae Radix. Their medicinal properties were mainly warm, cold, and calm, flavours were mainly pungent, sweet, and bitter, channel tropism were mainly liver, lung, and spleen channels. Most of the drugs were relieving superficies medicines. The system cluster analysis was divided into four groups of drug combinations, and 16 drug combinations with high support were found by association rule analysis. Conclusion The overall therapeutic principles of traditional Chinese medicine in the treatment of tension-type headache to dispel pathogenic wind and relieve pain, promote blood circulation for removing obstruction in collaterals, disperse stagnated liver qi and suppress hyperactive liver, invigorate spleen for resolving masses. Its medication regularity can provide reference for clinical treatment and new drug research and development.

Key words： Tension-type headache Traditional Chinese medicine Data mining Medication rules

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	WANG Qing LIU Meisi SHI Bowen WANG Yuyao ZHAO Shibo WANG Liwei ZHAO Yonglie

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WANG Qing LIU Meisi SHI Bowen WANG Yuyao ZHAO Shibo WANG Liwei ZHAO Yonglie. Exploration and discussion on the clinical medication rules of traditional Chinese medicine in the treatment of tension-type headache based on data mining[J]. 中国医药导报, 2022, 19(26): 5-8,23.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2022.26.01 OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I26/5

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