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| Application progress of repetitive transcranial magnetic stimulation in rehabilitation of upper limb motor dysfunction after stroke |
| WU Xiaofang1 LEI Juanjuan1 WU Qunqiang1 LIAO Chunhua1 JIA Binbin2 LIU Rui1#br# |
1.Department of Rehabilitation Medicine, the Second Affiliated Hospital of Air Force Medical University of Chinese People’s Liberation Army, Shaanxi Province, Xi’an 710038, China;
2.the Third Department of Internal Medicine, Zichang People’s Hospital, Shaanxi Province, Zichang 717300, China
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Abstract Residual upper limb motor dysfunction after stroke results in complete or partial loss of working ability and independent living ability, which seriously affects the quality of life of patients and brings heavy burden to their families and society. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique that uses a pulsed magnetic field on a specific cerebral cortex to alter the membrane potential of cortical cells and induce electrical currents, thereby affecting brain metabolism and neural electrical activity. rTMS has a positive effect on the rehabilitation of upper limb motor dysfunction after stroke, and its efficacy is related to many factors such as intervention period, target, stimulation mode, and individual differences of patients. This paper briefly introduces the research progress of rTMS for rehabilitation of upper limb motor dysfunction after stroke, in order to provide a detailed reference for clinical application.
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[1] Winstein CJ，Stein J，Arena R，et al. Guidelines for Adult Stroke Rehabilitation and Recovery [J]. Stroke，2016，47（6）：e89-e169.
[2] Micera S，Caleo M，Chisari C，et al. Advanced Neurotechnologies for the Restoration of Motor Function [J]. Neuron，2020，105（4）：604-620.
[3] Rossini PM，Burke D，Chen R，et al. Non-invasive electrical and magnetic stimulation of the brain，spinal cord，roots and peripheral nerves：Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee [J]. Clin Neurophysiol，2015，126（6）：1071-1107.
[4] Klomjai W，Katz R，Lackmy-vallee A. Basic principles of transcranial magnetic stimulation（TMS） and repetitive TMS （rTMS）[J]. Ann Phys Rehabil Med，2015，58（4）：208-213.
[5] Fisicaro F，Lanza G，Grasso AA，et al. Repetitive transcranial magnetic stimulation in stroke rehabilitation：review of the current evidence and pitfalls [J]. Ther Adv Neurol Disord，2019，12：1756286419878317.
[6] Van Lieshout EC，Jacobs LD，Pelsma M，et al. Exploring the experiences of stroke patients treated with transcranial magnetic stimulation for upper limb recovery：a qualitative study [J]. BMC Neurol，2020，20（1）：365.
[7] Adeyemo BO，Simis M，Macea DD，et al. Systematic review of parameters of stimulation，clinical trial design characteristics，and motor outcomes in non-invasive brain stimulation in stroke [J]. Front Psychiatry，2012，3：88.
[8] Stinear CM，Petoe MA，Byblow WD. Primary Motor Cortex Excitability During Recovery After Stroke：Implications for Neuromodulation [J]. Brain Stimul，2015，8（6）：1183-1190.
[9] Schambra HM. Repetitive Transcranial Magnetic Stimulation for Upper Extremity Motor Recovery：Does It Help? [J]. Curr Neurol Neurosci Rep，2018，18（12）：97.
[10] Matsuura A，Onoda K，Oguro H，et al. Magnetic stimulation and movement-related cortical activity for acute stroke with hemiparesis [J]. Eur J Neurol，2015，22（12）：1526-1532.
[11] Yoon KJ，Lee YT，Han TR. Mechanism of functional recovery after repetitive transcranial magnetic stimulation （rTMS） in the subacute cerebral ischemic rat model：neural plasticity or anti-apoptosis? [J]. Exp Brain Res，2011，214（4）：549-556.
[12] Yuan X，Yang Y，Cao N，et al. Promotion of Poststroke Motor-Function Recovery with Repetitive Transcranial Magnetic Stimulation by Regulating the Interhemispheric Imbalance [J]. Brain Sci，2020，10（9）：648.
[13] Hirakawa Y，Takeda K，Tanabe S，et al. Effect of intensive motor training with repetitive transcranial magnetic stimulation on upper limb motor function in chronic post-stroke patients with severe upper limb motor impairment [J]. Top Stroke Rehabil，2018，25（5）：321-325.
[14] Koganemaru S，Mima T，Thabit MN，et al. Recovery of upper-limb function due to enhanced use-dependent plasticity in chronic stroke patients [J]. Brain，2010，133（11）：3373-3384.
[15] 周哲，沈夏锋，熊莉，等.运动前区高频重复经颅磁刺激对脑卒中上肢功能康复的疗效[J].中国康复理论与实践，2020，26（6）：697-702.
[16] Di Pino G，Pellegrino G，Assenza G，et al. Modulation of brain plasticity in stroke：a novel model for neurorehabilitation [J]. Nat Rev Neurol，2014，10（10）：597-608.
[17] Ludemann-podubecka J，Bosl K，Nowak DA. Inhibition of the contralesional dorsal premotor cortex improves motor function of the affected hand following stroke [J]. Eur J Neurol，2016，23（4）：823-830.
[18] Tscherpel C，Hensel L，Lemberg K，et al. The differential roles of contralesional frontoparietal areas in cortical reorganization after stroke [J]. Brain Stimul，2020，13（3）：614-624.
[19] Gu SY，Chang MC. The Effects of 10-Hz Repetitive Transcranial Magnetic Stimulation on Depression in Chronic Stroke Patients [J]. Brain Stimul，2017，10（2）：270-274.
[20] Hong Y，Liu Q，Peng M，et al. High-frequency repetitive transcranial magnetic stimulation improves functional recovery by inhibiting neurotoxic polarization of astrocytes in ischemic rats [J]. J Neuroinflammation，2020，17（1）：150.
[21] Guan YZ，Li J，Zhang XW，et al. Effectiveness of repetitive transcranial magnetic stimulation（rTMS） after acute stroke：A one-year longitudinal randomized trial [J]. CNS Neuroscience & Therapeutics，2017，23（12）：940-946.
[22] Guo Z，Jin Y，Bai X，et al. Distinction of High- and Low-Frequency Repetitive Transcranial Magnetic Stimulation on the Functional Reorganization of the Motor Network in Stroke Patients [J]. Neural Plast，2021：8873221.
[23] Vabalaite B，Petruseviciene L，Savickas R，et al. Effects of High-Frequency （HF） Repetitive Transcranial Magnetic Stimulation （rTMS） on Upper Extremity Motor Function in Stroke Patients：A Systematic Review [J]. Medicina （Kaunas），2021，57（11）：1215.
[24] Wang Q，Zhang D，Zhao YY，et al. Effects of high-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex on motor recovery in severe hemiplegic stroke：A randomized clinical trial [J]. Brain Stimul，2020，13（4）：979-986.
[25] Du J，Tian L，Liu W，et al. Effects of repetitive transcranial magnetic stimulation on motor recovery and motor cortex excitability in patients with stroke：a randomized controlled trial [J]. Eur J Neurol，2016，23（11）：1666-1672.
[26] Ludemann-podubecka J，Bosl K，Theilig S，et al. The Effectiveness of 1 Hz rTMS Over the Primary Motor Area of the Unaffected Hemisphere to Improve Hand Function After Stroke Depends on Hemispheric Dominance [J]. Brain Stimul，2015，8（4）：823-830.
[27] Harvey RL，Edwards D，Dunning K，et al. Randomized Sham-Controlled Trial of Navigated Repetitive Transcranial Magnetic Stimulation for Motor Recovery in Stroke [J]. Stroke，2018，49（9）：2138-2146.
[28] Long H，Wang H，Zhao C，et al. Effects of combining high- and low-frequency repetitive transcranial magnetic stimulation on upper limb hemiparesis in the early phase of stroke [J]. Restor Neurol Neurosci，2018，36（1）：21-30.
[29] Chen Q，Shen D，Sun H，et al. Effects of coupling inhibitory and facilitatory repetitive transcranial magnetic stimulation on motor recovery in patients following acute cerebral infarction [J]. NeuroRehabilitation，2021，48（1）：83-96.
[30] Noh JS，Lim JH，Choi TW，et al. Effects and safety of combined rTMS and action observation for recovery of function in the upper extremities in stroke patients：A randomized controlled trial [J]. Restor Neurol Neurosci，2019，37（3）：219-230.
[31] Gong Y，Long XM，XU Y，et al. Effects of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation on motor function and cortex excitability in subacute stroke patients：A randomized controlled trial [J]. Clin Rehabil，2020：269215520972940.
[32] Graef P，Dadalt MLR，Rodrigues D，et al. Transcranial magnetic stimulation combined with upper-limb training for improving function after stroke：A systematic review and meta-analysis [J]. J Neurol Sci，2016，369：149-158.
[33] Litvak V，Zeller D，Oostenveld R，et al. LTP-like changes induced by paired associative stimulation of the primary somatosensory cortex in humans：source analysis and associated changes in behaviour [J]. Eur J Neurosci，2007， 25（9）：2862-2874.
[34] Chen X，Liu X，Cui Y，et al. Efficacy of functional magnetic stimulation in improving upper extremity function after stroke：a randomized，single-blind，controlled study [J]. J Int Med Res，2020，48（6）：300060520927881.
[35] 马明，蔡倩，徐亮，等.重复性外周神经磁刺激对脑卒中患者上肢屈肘肌痉挛的影响[J].中华物理医学与康复杂志，2017，39（2）：127-130.
[36] Zong X，Dong Y，Li Y，et al. Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity [J]. Transl Stroke Res，2020，11（3）：450-467.
[37] Zong X，Li Y，Liu C，et al. Theta-burst transcranial magnetic stimulation promotes stroke recovery by vascular protection and neovascularization [J]. Theranostics，2020， 10（26）：12090-12110.
[38] Volz LJ，Rehme AK，Michely J，et al. Shaping Early Reorganization of Neural Networks Promotes Motor Function after Stroke [J]. Cereb Cortex，2016，26（6）：2882-2894.
[39] Sui YF，Tong LQ，Zhang XY，et al. Effects of paired associated stimulation with different stimulation position on motor cortex excitability and upper limb motor function in patients with cerebral infarction [J]. J Clin Neurosci，2021，90：363-369.
[40] Chiu D，Mccane CD，Lee J，et al. Multifocal transcranial stimulation in chronic ischemic stroke：A phase 1/2a randomized trial [J]. J Stroke Cerebrovasc Dis，2020，29（6）：104816. |
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