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Professor Chen Yiping’s experience in the treatment of IgA nephropathy with the “woxuan sanjiao” |
ZHANG Quan CHEN Yiping ZHANG Xianwen SHENG Lingli WANG Lin▲ |
Department of Nephrology, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China |
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Abstract The treatment of IgA nephropathy is a research problem in the world. Professor Chen Yiping, a famous traditional Chinese medicine in Shanghai and the founder of the nephrology discipline of integrated traditional Chinese and western medicine in China, believes that the occurrence and development of IgA nephropathy are closely related to the sanjiao, and puts forward the treatment method of “woxuan sanjiao, divide and rule”. The secret of its treatment lies in dredging the qi and blood of the sanjiao, and the clinical syndrome attaches importance to the methods of reconciling shaoyang and benefiting qi for activating blood circulation. At the same time, in the different stages of IgA nephropathy, he proposed to apply reasonable methods such as dispersing the lung and relieving throat disorder, invigorating spleen for eliminating dampness, clearing heat and promoting diuresis to focus therapeutic goal on the different parts of the upper, middle and lower sanjiao, and eliminate the diffuse evil poison of the sanjiao. Professor Chen has accumulated rich clinical experience and outstanding curative effect by creating prescription and selecting drugs, combining Chinese and western ingredients, and paste prescription in sequence, and regulating the sanjiao and quenching “the kidney wind”.
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[1] Duan ZY,Cai GY,Chen YZ,et al. Aging promotes progression of IgA nephropathy:a systematic review and meta-analysis [J]. Am J Nephrol,2013,38(3):241-252.
[2] 王海燕.肾脏病学[M].北京:人民卫生出版社,2008:1008.
[3] Le W,Liang S,Hu Y,et al. Long-term renal survival and related risk factors in patients with IgA nephropathy:results form a cohort of 1155 cases in a Chinese adult population [J]. Nephrol Dial transplant,2012,27(4):1479-1485.
[4] 王琳.陈以平教授诊治中重症IgA肾病学术思想研究[J].中国中西医结合肾病杂志,2010,11(12):1043-1045.
[5] 沈莲莉,陈正,张璐芸,等.陈以平教授治疗中重症IgA肾病远期疗效的临床研究[J].中国中西医结合肾病杂志,2019,20(8):675-678.
[6] 张权,凌春燕,朱逸云,等.基于真实世界的中医药对IgA肾病肾功能保护作用研究[J].中国中医药信息杂志,2021,28(11):103-107.
[7] 张权,张先闻,王琳,等.从干预IgA1异常糖基化角度探讨中医“三焦”论治IgA肾病[J].中国中西医结合肾病杂志,2021,22(4):367-369.
[8] Yanagawa H,Suzuki H,Suzuki Y,et al. A panel of serum biomarkers differentiates IgA nephropathy from other renal diseases [J]. PLoS One,2014,9(5):e98081.
[9] 田秀娟,黄晨.IgA肾病免疫炎症发病机制研究进展[J].中华肾脏病杂志,2020,36(5):400-405.
[10] 王倩,杨丽平,占永立.黏膜免疫系统在IgA肾病发病机制的作用及中医认识进展[J].中国中西医结合肾病杂志,2018,19(1):81-83.
[11] 白雅雯,麻春杰,钱占红,等.湿热与IgA肾病黏膜免疫缺陷的相关性研究[J].中医药信息,2018,35(5):34-36.
[12] 孙红旭,卢嫣,王怡.“枢机不利”致IgA肾病机制探讨[J].辽宁中医杂志,2018,45(10):2068-2070.
[13] 殷敏,钟逸斐,邓跃毅.陈以平教授中西医结合治疗中重症IgA肾病经验[J].中国中西医结合肾病杂志,2009, 10(1):8-10.
[14] 须冰,王祎熙,陈以平.中医及中西医结合治疗IgA肾病疗效分析[J].中国中西医结合肾病杂志,2011,12(4):333-335.
[15] 蔡小凡,刘睿,陈永乐,等.中医及中西医结合方案治疗150例IgA肾病的疗效分析[J].中国中西医结合肾病杂志,2011,12(12):1094-1096.
[16] 高洪志,陈万佳,胡聃,等.中医药治疗免疫球蛋白A肾病Lee氏Ⅲ-Ⅴ级的疗效分析[J].世界临床药物,2017, 38(4):272-276.
[17] 张先闻,黄志强,王琳,等.肾平方阻断IgA肾病中循环免疫复合物诱导的人系膜细胞PDGF信号通路激活及增殖[C]//中国中西医结合学会肾脏疾病专业委员会2015年学术年会资料汇编,2015:856-857.
[18] 朱逸云,王琳,陈以平.基于“中医传承辅助平台”分析探讨陈以平教授治疗IgA肾病用药规律的研究[J].中华肾病研究电子杂志,2019,8(5):201-207.
[19] 黄婷.雷公藤治疗IgA肾病的系统评价[D].济南:山东中医药大学,2017.
[20] 朱彩凤,包自阳,朱斌,等.雷公藤内酯醇对IgA肾病大鼠血清IgA异常糖基化的影响[J].中国病理生理杂志,2009,25(1):186-187,193. |
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