脑梗死和脑出血1年复发风险比较和危险因素分析

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Abstract Objective To compare the recurrence risk of cerebral infarction and cerebral hemorrhage within one year and to analyze the clinical risk factors. Methods Eight hundred and sixteen stroke patients (592 cases of cerebral infarction and 224 cases of cerebral hemorrhage) hospitalized in the Department of Acupuncture and Moxibustion, Shenzhen Traditional Chinese Medicine Hospital from September 2017 to June 2019 were included. The demographic characteristics and control of risk factor of stroke were collected and followed up for one year. The recurrence risk of cerebral infarction and cerebral hemorrhage were compared by Kaplan-Meier method. The risk factors of cerebral infarction and cerebral hemorrhage recurrence were analyzed by single factor analysis, and then the Cox proportional risk regression model related to recurrence was established by stepwise regression method. Results After correction of age and gender，comparison of K-M curves between two groups showed statistically significant difference (P < 0.05). For cerebral infarction, the risk of recurrence was 1.872 times higher in patients with family history of stroke than patients without family history of stroke (95%CI: 1.063-3.311, P = 0.031), and 1.464 times higher in patients with poor blood pressure control than in patients with good blood pressure control (95%CI: 1.058-2.018, P = 0.020). For intracerebral hemorrhage, patients with family history of stroke had 4.685 times higher risk of recurrence than those without family history of stroke (95%CI: 1.372-16.003, P = 0.014), and patients with poor blood glucose control had 2.961 times higher risk of recurrence than those with good blood glucose control (95%CI: 1.459-6.010, P = 0.003), the risk of recurrence in patients who still drank alcohol was 2.719 times that of those who did not drink alcohol (95%CI: 1.223-6.046, P = 0.014). Conclusion The recurrence rate of cerebral infarction is higher than that of cerebral hemorrhage in stroke patients with one-year onset. Poor blood pressure control is an independent risk factor for recurrence of cerebral infarction, while poor glycemic control and alcohol consumption behavior are independent risk factors for recurrence of cerebral hemorrhage, and interventions targeting these factors are needed to reduce the risk of stroke recurrence.

Key words： Cerebral infarction Cerebral hemorrhage Survival analysis Risk factors Cox regression

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	ZHUO Yuanyuan1 WANG Xinru2 HUANG Congcong2 PI Min1 YUAN Weiqu1 LI Kailin2 YU Haibo1

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ZHUO Yuanyuan1 WANG Xinru2 HUANG Congcong2 PI Min1 YUAN Weiqu1 LI Kailin2 YU Haibo1. Comparison for recurrence of cerebral infarction and cerebral hemorrhage in one year and analysis of risk factors[J]. 中国医药导报, 2022, 19(23): 74-78.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I23/74

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