急性心肌梗死患者碎裂QRS波与自主神经功能及左室重构的相关性

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Abstract Objective To investigate the correlation between fragmented QRS (fQRS) waves and autonomic function and left ventricular remodeling in patients with acute myocardial infarction (AMI). Methods A total of 114 patients with AMI admitted to Hospital of Beijing Armed Police Corps from January 2015 to June 2021 were selected and they were divided into fQRS group (51 cesea) and non-fQRS group (63 cases) according to the presence or absence of fQRS. The baseline data, heart rate variability parameters, and left ventricular function indexes were compared between the two groups, and the correlation of fQRS with heart rate variability parameters and left ventricular function indexes were analyzed. Results The proportion of ST-segment elevation myocardial infarction, total cholesterol, low density lipoprotein cholesterol, serum creatinine, blood urea nitrogen, blood uric acid, cardiac troponin I, creatine phosphokinase, creatine kinase isozyme, ventricular septal thickness (IVST), and left ventricular posterior wall thickness (LVPW) in fQRS group were higher than those in non-fQRS group. High density lipoprotein cholesterol, low spectral power, very low spectral power, low spectral power to high spectral power ratio (LF/HF), standard deviation of 24 h normal sinus R-R interval (SDNN), mean deviation of every five minutes sinus R-R interval (SDANN), and left ventricular ejection fraction (LVEF) were lower than those in the non-fQRS group, the differences were statistically significant (P < 0.05). fQRS was negatively correlated with low spectral power, very low spectral power, LF/HF, SDNN, SDANN and LVEF (r = -0.364, -0.409, -0.365, -0.428, -0.355, -0.423, P < 0.001), it was positively correlated with IVST and LVPW (r = 0.457, 0.544, P < 0.001). FQRS had no correlation with high spectral power (r = -0.141, P ＞ 0.05). Conclusions Cardiac autonomic dysfunction is evident in AMI patients with fQRS and is closely associated with left ventricular remodelling.

Key words： Acute myocardial infarction Fragmented QRS waves Autonomic function Left ventricular remodeling

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	HU Yanli1 SHAN Qing2 XIAO Sa1 HAN Yuhua1

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HU Yanli1 SHAN Qing2 XIAO Sa1 HAN Yuhua1. Correlation of fragmented QRS waves with autonomic function and left ventricular remodeling in patients with acute myocardial infarction[J]. 中国医药导报, 2022, 19(23): 53-56,78.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I23/53

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