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Research progress on rationality of lymph node status involved in cervical cancer staging system |
CHANG Hong WU Yumei#br# |
Department of Gynecology Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China
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Abstract Cervical cancer is the most common malignant tumor of the female reproductive system. In the past, clinical staging was used, in 2018, the International Federation of Obstetrics and Gynecology first proposed to set the lymph node metastasis diagnosed by imaging and pathology as stage ⅢC, reflecting that lymph node positivity was independent risk factors for prognosis of patients with cervical cancer. At the same time, the number of lymph node metastases, the size of the local tumor and the degree of parametrial invasion are also important determinants of prognosis. Imaging can diagnose lymph node metastasis by color doppler ultrasound, CT, MRI, PET/CT, etc. After lymphadenectomy whether or not combine abdominal aortic lymphadenectomy, patients with locally advanced disease can also undergo pathological diagnosis of lymph node metastasis after retroperitoneal lymphadenectomy. Concurrent chemoradiotherapy is recommended for the treatment of patients with confirmed lymph node metastasis. This article reviews the studies on the involvement of lymph node status in the staging of cervical cancer.
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