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Epidemiology and treatment status of Graves disease in children |
SHI Hongjiao ZHANG Yili ZHAO Tong CUI Lanwei#br# |
Department of Pediatrics, the First Affiliated Hospital of Harbin Medical University, Heilongjiang Province, Harbin 150000, China
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Abstract Graves disease is a common autoimmune disease with unknown pathogenesis. The incidence of children is significantly lower than that of adults, the incidence varies from place to place, but the overall trend is increasing year by year. The most common laboratory test is the change of thyroid function, and the clinical manifestations include hypermetabolism symptoms and other manifestations such as accelerated growth. At present, oral Methimazole is the first choice for the treatment of children with Graves disease, which is convenient to treat and has few adverse reactions. For children who have not improved after long-term oral antithyroid drug treatment, iodine therapy can be considered, which will significantly improve the remission rate of children. This article reviews the status of Graves disease in children.
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