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| Clinical effect of Fufang Zilian Ointment combined with Hydrocortisone Butyrate Cream in the treatment of subacute infantile eczema with spleen deficiency and dampness accumulation syndrome |
| GONG Ke1 GUO Jianhui1 DU Kaiqing1 GUO Wen1 ZHANG Xianzhe1 ZHANG Man1 CUI Yaxin2 LIU Jiayao2#br# |
1.Department of Dermatology, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Hebei University of Traditional Chinese Medicine, Hebei Province, Cangzhou 061000, China;
2.Graduate School, Chengde Medical College, Hebei Province, Chengde 067000, China |
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Abstract Objective To observe the clinical effect of Fufang Zilian Ointment combined with Hydrocortisone Butyrate Cream in the treatment of subacute infantile eczema with spleen deficiency and dampness accumulation syndrome. Methods A total of 100 cases of subacute infantile eczema with spleen deficiency and dampness accumulation syndrome from December 2020 to July 2021 in Department of Dermatology, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Hebei University of Traditional Chinese Medicine were selected. They were divided into treatment group and control group, with 50 cases in each group. The control group was treated with Hydrocortisone Butyrate Cream, and treatment group was treated with Fufang Zilian Ointment on the basis of control group. After two weeks of treatment, the clinical efficacy of two groups was observed; eczema area and severity index (EASI) score, traditional Chinese medicine syndrome score, transepidermal waterloss (TEWL) and the occurrence of adverse reactions in two groups were compared; two weeks after the end of treatment, the recurrence rate was counted. Results After two weeks of treatment, EASI score, traditional Chinese medicine syndrome score and TEWL in two groups were lower than those before treatment, and treatment group was lower than control group, and the differences were statistically significant (P < 0.05). The clinical efficacy of treatment group was better than that of control group, and the difference was statistically significant (P < 0.05). The recurrence rate of treatment group was lower than that of control group, and the difference was statistically significant (P < 0.05). No obvious discomfort and no adverse events occurred in the two groups during treatment. Conclusion Fufang Zilian Ointment combined with Hydrocortisone Butyrate Cream can significantly improve the skin lesions and symptoms of subacute infantile eczema with spleen deficiency and dampness accumulation syndrome, with good clinical efficacy and low recurrence rate, which is worthy of clinical promotion and further research.
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| Cite this article: |
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GONG Ke1 GUO Jianhui1 DU Kaiqing1 GUO Wen1 ZHANG Xianzhe1 ZHANG Man1 CUI Yaxin2 LIU Jiayao2. Clinical effect of Fufang Zilian Ointment combined with Hydrocortisone Butyrate Cream in the treatment of subacute infantile eczema with spleen deficiency and dampness accumulation syndrome[J]. 中国医药导报, 2022, 19(21): 107-110.
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| URL: |
| https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I21/107 |
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