急性缺血性卒中患者血管内治疗后早期癫痫发作的危险因素分析

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Abstract Objective To investigate the risk factors for early seizures after endovascular therapy for acute ischemic stroke. Methods A retrospective summary was made of 184 patients with acute ischemic stroke who underwent endovascular treatment in the Department of Neurology, Nanning Second People’s Hospital from June 2019 to December 2021. The patients were divided into 36 cases in the epilepsy group and 148 cases in the non-epileptic group according to whether they were complicated with epilepsy. Neurological deficits were assessed using the National Institutes of Health stroke scale (NIHSS) score, and the Glasgow coma scale (GCS) were used to assess the degree of disturbance of consciousness. Logistic regression was used to analyze the possible risk factors of early seizures after endovascular therapy for acute ischemic stroke. Results The proportion of epilepsy group in age ≤65 years old, preoperative NIHSS score＞11 points, preoperative GCS≤8 points, diabetes, anterior circulation lesions, mechanical thrombectomy and aspiration, hemorrhagic transformation, and operation duration＞1 h were higher than those of the non-epilepsy group (P < 0.05). The results of multivariate logistic regression analysis showed that the preoperative NIHSS score＞11 points, preoperative GCS≤8 points, mechanical thrombectomy, hemorrhagic transformation and aspiration, operation time＞1 h were independent risk factors for acute ischemic stroke complicated with early epilepsy after endovascular treatment (P ＜ 0.05). Conclusion Disease severity, surgical method, hemorrhagic transformation and duration of surgery are risk factors for early seizures in patients undergoing endovascular interventional therapy in the acute phase, and it is worthy of clinical attention.

Key words： Acute ischemic stroke Endovascular treatment Early epileptic seizures

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	QIN Bailing LI Tong HU Minting WEI Chunyan

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QIN Bailing LI Tong HU Minting WEI Chunyan. Analysis of risk factors for early seizures after endovascular therapy for acute ischemic stroke[J]. 中国医药导报, 2022, 19(21): 49-52.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I21/49

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