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| Investigation on the detection rate and risk factors of dyslipidemia in the physical examination population of the Zhuang nationality in Nanning City |
| HUANG Yunhua1 GAN Min2 QIN Yuanyuan1 ZHAI Lujie2 CHEN Qingyun2 LIN Faquan1 SUN Zilin3 WANG Peng2▲ |
1.Department of Clinical Laboratory, the First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530021, China; 2.Department of Health Management, the First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530021, China;
3.Department of Endocrinology, Zhongda Hospital, Southeast University, Jiangsu Province, Nanjing 210009, China |
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Abstract Objective To study the detection rate and risk factors of dyslipidemia in the population of the Zhuang nationality in Nanning City, and provide a theoretical basis for the prevention and treatment of dyslipidemia. Methods The baseline data of urban and rural Zhuang residents aged 20-70 from Nanning in 2017 using the Guangxi project of National Key Research and Development Projects was analyzed. A random stratified cluster sampling method was used to enroll the research objects, a total of 2019 cases were enrolled for questionnaire surveys, physical examinations, and blood index tests. After excluding the invalid population, 1982 subjects were finally included. The subjects were divided into dyslipidemia group and non-dyslipidemia group according to the levels of blood lipids. The differences of various indexes between dyslipidemia group and non-dyslipidemia group were compared. The risk factors of dyslipidemia were analyzed by using the binary logistic regression. Results A total of 815 cases of abnormal lipids were examined, accounting for 41.1% of the total number. The detection rates of hypertriglyceridemia and low high-density lipoprotein cholesterol in men were higher than those in women, and the differences were statistically significant (P ＜ 0.05). The age, the ration of tea drinking, high fat intake, snoring, body mass index, diastolic blood pressure, systolic blood pressure, leukocyte, hemoglobin, 2-hour postprandial blood glucose, glycosylated hemoglobin, fasting blood glucose, creatinine, urea nitrogen, and uric acid in the dyslipidemia group were higher than those in the non-dyslipidemia group, and the percentage of neutrophils in the dyslipidemia group was lower than that in the non-dyslipidemia group, and the differences were statistically significant (P ＜ 0.05). The results of binary logistic regression analysis showed that age, body mass index, hemoglobin, 2-hour postprandial blood glucose, uric acid, and urea nitrogen were the independent risk factors for dyslipidemia (P ＜ 0.05), and the percentage of neutrophils was the protective factor for dyslipidemia (P ＜ 0.05). Conclusion The detection rate of dyslipidemia in the Zhuang nationality in Nanning is relatively high. The increased levels of age, body mass index, hemoglobin, 2-hour postprandial blood glucose, uric acid, and urea nitrogen are the risk factors for dyslipidemia.
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