肺和肠道微生物群落与哮喘的研究进展

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Abstract Asthma is a common chronic respiratory disease with an increasing incidence year by year. Its clinical characteristics, immunology, and molecular etiology often vary from person to person. In recent years, with the rise of microbial metabolomics analysis, it has been found that microbial communities of lung and intestinal play an important role in the development, regulation, and maintenance of healthy immune response, thus giving birth to the concept of “entero-pulmonary axis”. Microbial communities of lung and intestinal affects the development, clinical features, and treatment response of asthma. The effects and mechanisms of different microbial communities on bronchial asthma are still unclear. In this paper, we review the relationship between microbial communities of lung and intestinal and their effects on asthma, providing new ideas for the diagnosis and personalized treatment of asthma.

Key words： Asthma Entero-pulmonary axis Intestinal flora Pulmonary flora Microbial community

Fund:湖北省卫生健康委员会科研项目（WJ2019M2 31）。

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	LI Liao1 YANG Lei2

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LI Liao1 YANG Lei2. Research advance of microbial communities of lung and intestinal in asthma[J]. 中国医药导报, 2022, 19(17): 42-45.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I17/42

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