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| Research on the medication rules of Professor Jiang Hongjiang in the treatment of knee arthralgia disease based on data mining technology |
| SHI Wei1 HOU Yan2 LI Lei2 YU Xin2 ZOU Debao2 WANG Zhizhou1 WANG Jie1 JIANG Hongjiang2 |
1.Graduate School, Anhui University of Chinese Medicine, Anhui Province, Hefei 230000, China;
2.the Third Department of Arthrosis, Shandong Wendeng Osteopathic Hospital, Shandong Province, Weihai 264400, China |
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Abstract Objective To study Professor Jiang Hongjiang’s medication rules and academic characteristics in the treatment of knee arthralgia disease based on the method of prescription data mining, and pass it on in a timely manner. Methods The medical records of knee arthralgia disease treated by Professor Jiang Hongjiang in Shandong Wendeng Osteopathic Hospital from September 2020 to April 2021 were collected and the prescription data were collected by a designated person. The database of medical records of “Professor Jiang Hongjiang’s experience in knee treatment” was established on the ancient and modern of cloud platform of medical records. Data mining analysis was used to analyze the frequency, nature and flavour, and channel tropism, and efficacy of traditional Chinese medicine in medical records, and correlation analysis, complex network analysis and cluster analysis were used to obtain the compatibility rules, core combination, and core cluster of traditional Chinese medicine. Results A total of 82 medical records were collected, including 68 traditional Chinese medicine. The top three traditional Chinese medicine frequency were Achyranthis Bidentatae Radix, Gardeniae Fructus Praeparatus, and Chuanxiong Rhizoma. The drug properties were mainly flat and warm; the drug tastes were mainly bitter, sweet and bitter; channel tropism were mainly liver, lung, kidney, heart, and spleen channel; the effect was mainly to tonify liver and kidney, strengthen muscles and bones, dispel wind and relieve pain. From the compatibility and association rules of traditional Chinese medicine, it could be concluded that the traditional Chinese medicine combinations mainly include tonifying liver and kidney, promoting blood circulation for removing blood stasis, removing dampness and relieving pain. Through the complex network analysis, the core recipe combination was Achyranthis Bidentatae Radix, Gardeniae Fructus Praeparatus, Angelicae Sinensis Radix, salt Eucommiae Cortex, Astragali Radix, Dipsaci Radix piece, Chuanxiong Rhizoma, Luffae Fructus Retinervus, stir-fried Myrrha, and Forsythiae Fructus. Four core clustering groups were obtained by clustering analysis. Conclusion Professor Jiang Hongjiang’s main treatment methods for knee arthralgia disease are tonifying liver and kidney, strengthening muscles and bones, dispelling wind and relieving pain, promoting blood circulation and removing stasis, which is of great benefit to clinical medication and experience inheritance.
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