不同中医证型寻常性银屑病患者睡眠质量、瘙痒程度与病情严重程度的相关性研究

Abstract
Figure/Table
References (26)
Related Citation (15)

Download: PDF (550 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the correlation between sleep quality, itching degree, and severity of psoriasis vulgaris patients with different traditional Chinese medicine syndromes. Methods From February to September 2021, 112 patients with psoriasis vulgaris were selected from the outpatient department of Dongzhimen Hospital of Beijing University of Chinese Medicine, they were divided into blood heat group, blood stasis group, and blood dryness group according to the dialectical classification of traditional Chinese medicine. They were investigated by sleep quality index (PSQI), insomnia severity index (ISI), visual analogue scales (VAS), and psoriasis area and severity index (PASI). Another 112 healthy volunteers were selected as the control group. Results Compared with blood heat group, ISI, and VAS scores were lower in blood stasis group, PSQI, PASI, and VAS scores were lower in blood dryness group (P ＜ 0.05). Compared with blood stasis group, PASI score in blood dryness group was lower (P ＜ 0.05). The subjective sleep quality, sleep time, and sleep efficiency scores of blood heat group were higher than those of control group (P ＜ 0.05). The sleep time scores of blood heat group, blood stasis group, and blood dryness group were higher than those of control group (P ＜ 0.05). The sleep disturbance score of blood heat group was higher than that of blood stasis group and control group (P ＜ 0.05). The daytime dysfunction score of blood heat group was higher than that of blood stasis group and control group, and the daytime dysfunction score of blood dryness group was lower than that of blood heat group and control group (P ＜ 0.05). PSQI, VAS scores were positively correlated with PASI scores in blood heat group (P ＜ 0.05). Conclusion Different traditional Chinese medicine syndromes have different sleep quality, pruritus degree, and severity of disease. Blood dryness syndrome mainly to improve sleep quality, blood heat syndrome mainly to relieve pruritus, blood stasis syndrome mainly to treat the primary disease, could achieve better curative effect.

Key words： Psoriasis vulgaris Traditional Chinese medicine syndrome Sleep quality Correlation Epidemiological investigation

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	TAN Meng GAO Yuexuan XU Jing DUAN Xingwu

Cite this article:

TAN Meng GAO Yuexuan XU Jing DUAN Xingwu. Study on the relationship between sleep quality, itching degree, and severity of psoriasis vulgaris patients with different traditional Chinese medicine syndromes[J]. 中国医药导报, 2022, 19(15): 125-128.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I15/125

[1] 丁晓岚，王婷琳，沈佚葳，等.中国六省市银屑病流行病学调查[J].中国皮肤性病学杂志，2010，24（7）：598-601.
[2] 谢秀丽，王洋洋，闫玉红，等.银屑病临床指南国际制定现状分析[J].中国皮肤性病学杂志，2019，33（11）：1323-1327.
[3] 赵辨.中国临床皮肤病学[M].南京：江苏科学技术出版社，2010：1011.
[4] 中华中医药学会皮肤科分会.皮肤科分会银屑病中医治疗专家共识（2017年版）[J].中国中西医结合皮肤性病学杂志，2018，17（3）：273-277.
[5] Fredriksson T，Pettersson U. Severe psoriasis—oral therapy with a new retinoid [J]. Dermatologica，1978，157（4）：238-244.
[6] Reich A，Heisig M，Phan N，et al. Visual analogue scale：evaluation of the instrument for the assessment of pruritus [J]. Acta Derm Venereol，2012，92（5）：497-501.
[7] 路桃影，李艳，夏萍，等.匹兹堡睡眠质量指数的信度及效度分析[J].重庆医学，2014，43（3）：260-263.
[8] Morin CM，Belleville G，Bélanger L，et al. The Insomnia Severity Index：psychometric indicators to detect insomnia cases and evaluate treatment response [J]. Sleep，2011，34（5）：601-608.
[9] 邓丙戌，姜春燕，王萍，等.银屑病的中医证候分布及演变规律[J].中医杂志，2006（10）：770-772.
[10] 姜桂仙，崔炳南.660例寻常型银屑病中医体质与中医证型分布规律研究[J].北京中医药，2012，31（10）：723-726.
[11] 谢知音，白彦萍，杨顶权.银屑病中医体质与辨证分型的相关性研究[J].中华中医药杂志，2009，24（6）：823-825.
[12] 王丽新，段行武.银屑病中医体质研究述评[J].中医杂志，2015，56（23）：2060-2063.
[13] 冯娟，宫玉艳，李好勋，等.全国五省市一般人群中医体质流行病学调查[J].中华中医药杂志，2016，31（11）：4722-4725.
[14] 张丽，杨雪琴，程娟，等.126例寻常型银屑病患者的睡眠质量调查及影响因素分析[J].解放军医学杂志，2009， 34（3）：254-255.
[15] Melikoglu M. Sleep Quality and its Association with Disease Severity in Psoriasis [J]. Eurasian J Med，2017，49（2）：124-127.
[16] 闫玉红，卢传坚，禤国维.寻常型银屑病核心病机探讨[J].辽宁中医杂志，2012，39（6）：1013-1015.
[17] 程萍，贾苇雪，李诚让.银屑病瘙痒机制的研究进展[J].中国皮肤性病学志，2021，35（4）：449-453.
[18] 朱定仙，吴银华，白娟，等.银屑病的瘙痒特征及相关因素分析[J].中国中西医结合皮肤性病学杂志，2017，16（5）：412-414.
[19] Weisshaar E. Pruritus und Psoriasis [J]. Der Hautarzt，2012，63（7）：547-552.
[20] Prignano F，Ricceri F，Pescitelli L，et al. Itch in psoriasis：epidemiology，clinical aspects and treatment options [J]. Clin Cosmet Investig Dermatol，2009，2：9-13.
[21] 魏淑，樊茜茜，平延培，等.失眠类型、中医证候与病程相关性的临床观察[J].长春中医药大学学报，2020，36（2）：301-304.
[22] 邢陈，宋伦.昼夜节律在调控免疫系统功能中的作用[J].军事医学，2017，41（3）：233-236.
[23] 徐孝平，潘永明，冷晓霞，等.睡眠剥夺对大鼠抗氧化应激的影响及中药的干预作用[J].浙江中医药大学学报，2011，35（2）：234-237.
[24] 税云华，张兰，雷光磊，等.臭氧大自血法对睡眠剥夺大鼠褪黑素及氧化应激指标的影响[J].实验动物与比较医学，2020，40（2）：110-115.
[25] 李雪丽，张斌.睡眠障碍与焦虑抑郁障碍的联系[J].中国临床医生杂志，2018，46（2）：131-133.
[26] 杨健，谷峰.“肝藏血，血舍魂”与睡眠障碍辨治[J].实用中医内科杂志，2019，33（3）：63-65.