基于知识图谱分析近10年雷公藤甲素的研究趋势与热点

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Abstract Objective To explore the development trend and hotspots of triptolide research in recent ten years in China through bibliometric visualization analysis. Methods The literatures related to triptolide included in Chinese National Knowledge Infrastructure from January 2011 to October 2021 were searched, and the included research institutions, authors and keywords were visually analyzed by CiteSpace software. Results The numbers of triptolide-related literature published was stable; the research institutions were mostly Chinese medicine universities and pharmacology-related laboratories, with less inter-institutional cooperation; the authors with the most number of articles were Liu Jianqun, Que Huiqing and Xu Wei, and no core team has been formed in China; the top three keywords in terms of frequency were “apoptosis”, “proliferation”, and “rheumatoid arthritis”, with 12 clusters of keywords and ten emergent words. Conclusion The number of triptolide-related articles issued in the past decade is stable, and the disease types involved in the research are constantly enriched, and preclinical research centered on anti-tumor and oxidative emergency is the hotspot of triptolide research in recent years.

Key words： Triptolide Apoptosis Proliferation Rheumatoid arthritis Tumor CiteSpace

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	YUAN Bo1 ZHI Kai2 CUI Weilu1 ZHANG Xieyu1 GE Lin1 CAO Wei3

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YUAN Bo1 ZHI Kai2 CUI Weilu1 ZHANG Xieyu1 GE Lin1 CAO Wei3. Analysis of research trends and hotspots of triptolide in recent ten years based on knowledge graph#br#[J]. 中国医药导报, 2022, 19(15): 23-28.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I15/23

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