不同诊断标准下急性缺血性脑卒中肌少症患病率研究

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Abstract Objective To compare the prevalence of acute ischemic stroke sarcopenia under different diagnostic criteria, and to explore the consistency and diagnostic efficacy of each diagnostic criteria. Methods A total of 117 patients of acute ischemic stroke in the encephalopathy department of Guangdong Provincial Hospital of Traditional Chinese Medicine from July 2020 to May 2021 were selected. Sarcopenia was diagnosed using the Asian Working Group for Sarcopenia (AWGS), the European Working Group on Sarcopenia in the elderly (EWGSOP), the International Working Group on Sarcopenia (IWGS), and the Foundation for the National Institutes of Health (FNIH), respectively. The general data of the patients were collected, grip strength, skeletal muscle mass of limbs were measured, and body mass index (BMI) was calculated. Concordance, sensitivity and specificity between diagnostic criteria were calculated. Results The prevalence of acute ischemic stroke sarcopenia under AWGS, EWGSOP, IWGS, and FNIH criteria were 40.2%, 33.3%, 44.4%, and 8.5%, respectively. With AWGS as the standard, the consistency rate with EWGSOP was 93.16% (Kappa = 0.97, P < 0.01), the sensitivity was 100.0%, and the specificity was 89.7%; the concordance rate with IWGS was 95.72% (Kappa = 0.99, P < 0.01), the sensitivity was 90.4%, and the specificity was 100.0%; the concordance rate with FNIH was 64.96% (Kappa = 0.06, P < 0.01), the sensitivity was 80.0%, and the specificity was 63.6%. Conclusion IWGS has the highest detection rate of sarcopenia in acute ischemic stroke, and the detection rate of FNIH is significantly lower than the other three diagnostic criteria; AWGS, EWGSOP, and IWGS have good consistency in the diagnosis of acute ischemic stroke sarcopenia, AWGS criteria have better sensitivity and specificity, and FNIH criteria have poor consistency with the other three diagnostic criteria.

Key words： Stroke Sarcopenia Prevalence Diagnostic criteria

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	CHEN Rui1 LIAO Ruotong1 LUO Wanghui2 LIANG Hao3 XIAO Hui4 GUO Jianwen3 WEI Lin4

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CHEN Rui1 LIAO Ruotong1 LUO Wanghui2 LIANG Hao3 XIAO Hui4 GUO Jianwen3 WEI Lin4. Prevalence of sarcopenia in acute ischemic stroke using different diagnostic criteria#br#[J]. 中国医药导报, 2022, 19(14): 121-124,129.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2022/V19/I14/121

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